multidrug effflux MFS transporter [Listeria monocytogenes].

LOCUS       WP_010990067             396 aa            linear   BCT 31-MAR-2023
ACCESSION   WP_010990067
VERSION     WP_010990067.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 396)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 396)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022939
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..396
                     /product="multidrug effflux MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43478
     Region          12..374
                     /region_name="MFS_MdfA_MDR_like"
                     /note="Multidrug transporter MdfA and similar multidrug
                     resistance (MDR) transporters of the Major Facilitator
                     Superfamily; cd17320"
                     /db_xref="CDD:340878"
     Site            order(22..23,26..27,51,54..55,112,143,146..147,229,232,
                     352)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340878"
ORIGIN      
        1 meknietkki nlallvclvg fpqisetiyt pslteiakgy gvslnlaqmt lsiyflafav
       61 gvffwgvssd flgrrkamnf gifiyilgcf aclfsnnitm lfigrfvqaf gastgsvttq
      121 tilrdnyhgn drhhlfakis aalafspaig pliggfigqy ygfrvvflfl vvmgmillfw
      181 slkrlpetkt vnatsfsvqk ivvigkkmif drytiafgal igifngilfs yyseaptifi
      241 erfhlnqsqy gfmgcavama tilgawlsnw rlmqnsphki ikegillaii gtlalsvvai
      301 fpltnqvily ilfisiilag igmalpncls lalvkfqeaa gtasaflslg yyvivslctf
      361 figvlhsgsm lvfpsfclvl lliallciki atrnnr