Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

multidrug efflux MFS transporter Lde [Listeria monocytogenes].


LOCUS       WP_010990057             402 aa            linear   BCT 11-APR-2024
ACCESSION   WP_010990057
VERSION     WP_010990057.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 402)
  AUTHORS   Godreuil,S., Galimand,M., Gerbaud,G., Jacquet,C. and Courvalin,P.
  TITLE     Efflux pump Lde is associated with fluoroquinolone resistance in
            Listeria monocytogenes
  JOURNAL   Antimicrob. Agents Chemother. 47 (2), 704-708 (2003)
   PUBMED   12543681
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to
            CAD00954.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR007178
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..402
                     /gene="lde"
     Protein         1..402
                     /product="multidrug efflux MFS transporter Lde"
                     /calculated_mol_wt=43332
     Region          11..389
                     /region_name="MFS_MdtG_MDR_like"
                     /note="Multidrug resistance protein MdtG and similar
                     multidrug resistance (MDR) transporters of the Major
                     Facilitator Superfamily; cd17391"
                     /db_xref="CDD:340949"
     Site            order(18..19,22..23,26,63,113..114,116..118,121,140,
                     143..144,147,220,223..224,227..229,232,263,267,316..317,
                     321,325,341,344..345,348..349,352)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340949"
ORIGIN      
        1 menwkknlyv vwvgcfltgt glnlimpflp lyieelgvhn pdqvsmwsgi alsstflvsa
       61 imspiwgkla dqkgrrimll raalgmaiam ilmglvsnvy qfvglrllmg ifsgyistan
      121 aliatqvprh rsgwalgals taavsgvlig pliggalsdt fgvrpvfyit gvlllgsffl
      181 tlffvkekft pvekkemrsg kevflslknp gliislfitt mmiqiasnsv npiltlyvrd
      241 lagnaqniaf isgmiasvpg vaaliaaprl grwgdrigse rillgaligs mllqipmafa
      301 qnplqlgilr fllgltdgal lpavqslltk ntprevagri fgynqsfqyi gnvigplvgs
      361 svaahfgygd vflvvagfif invlisfyfn rkmhgekgnh an