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LOCUS WP_010990046 579 aa linear BCT 16-JUN-2024 ACCESSION WP_010990046 VERSION WP_010990046.1 KEYWORDS RefSeq. SOURCE Listeria monocytogenes ORGANISM Listeria monocytogenes Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria. REFERENCE 1 (residues 1 to 579) AUTHORS Mironov,A., Seregina,T., Shatalin,K., Nagornykh,M., Shakulov,R. and Nudler,E. TITLE CydDC functions as a cytoplasmic cystine reductase to sensitize Escherichia coli to oxidative stress and aminoglycosides JOURNAL Proc Natl Acad Sci U S A 117 (38), 23565-23570 (2020) PUBMED 32900959 REFERENCE 2 (residues 1 to 579) AUTHORS Pittman,M.S., Robinson,H.C. and Poole,R.K. TITLE A bacterial glutathione transporter (Escherichia coli CydDC) exports reductant to the periplasm JOURNAL J Biol Chem 280 (37), 32254-32261 (2005) PUBMED 16040611 REFERENCE 3 (residues 1 to 579) AUTHORS Pittman,M.S., Corker,H., Wu,G., Binet,M.B., Moir,A.J. and Poole,R.K. TITLE Cysteine is exported from the Escherichia coli cytoplasm by CydDC, an ATP-binding cassette-type transporter required for cytochrome assembly JOURNAL J Biol Chem 277 (51), 49841-49849 (2002) PUBMED 12393891 REFERENCE 4 (residues 1 to 579) AUTHORS Cook,G.M., Membrillo-Hernandez,J. and Poole,R.K. TITLE Transcriptional regulation of the cydDC operon, encoding a heterodimeric ABC transporter required for assembly of cytochromes c and bd in Escherichia coli K-12: regulation by oxygen and alternative electron acceptors JOURNAL J Bacteriol 179 (20), 6525-6530 (1997) PUBMED 9335308 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: TIGR02868.1 Evidence Source :: JCVI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..579 /organism="Listeria monocytogenes" /db_xref="taxon:1639" gene 1..579 /gene="cydC" Protein 1..579 /product="thiol reductant ABC exporter subunit CydC" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_component="GO:0055051 - ATP-binding cassette (ABC) transporter complex, integrated substrate binding [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0033230 - ABC-type cysteine transporter activity [Evidence IEA]" /GO_function="GO:0050456 - cystine reductase activity [Evidence IEA]" /GO_process="GO:0033228 - cysteine export across plasma membrane [Evidence IEA]" /GO_process="GO:0045454 - cell redox homeostasis [Evidence IEA]" /calculated_mol_wt=64967 Region 5..573 /region_name="CydC" /note="ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones]; COG4987" /db_xref="CDD:444011" ORIGIN 1 mrksswiipy ikenrglfll viflgtltfa sagalmftsg hlisksslmp esimavyist 61 vgvrafgimr svsryverls shslvlrile kmrvrlyrll epqalllksr yktgdilgll 121 agdiehlqnf ylttmlpaiv slvlyagvvi algafsipfa alfvlligll vlvlpwvsll 181 yargknaylk qgrnslyqkf tdavfgisdw kfsgrektfi snyekdeadm lrtenkqfhf 241 vnwrdffsql vvgfmvivmv ywstaesrdg afsgtliaaf vlaimalaea fvpvssaisd 301 kslyqdslar ldkiedpalp tfeeetkeie rintenvvlk aenltfayde kspeilngfd 361 ftlqqgekva iigrsgtgks tflklvqgal lptagkvtmn dveveklrpq ipeltsmlnq 421 kahlfsttvl nnirlgnqda sdeevyeaak kvqlhdfims mpdgyhtqms emgerfsgge 481 rgrialaril lqntpivild eptvgldpit erdllatife tladksliwv thhlvgaekm 541 drvlfleegk tlmegphael maeeprykrl yqldrpiel