aldo/keto reductase [Listeria monocytogenes].

FASTA View on NCBI
LOCUS       WP_010990025             283 aa            linear   BCT 25-JUL-2024
ACCESSION   WP_010990025
VERSION     WP_010990025.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 283)
  AUTHORS   Hyndman,D., Bauman,D.R., Heredia,V.V. and Penning,T.M.
  TITLE     The aldo-keto reductase superfamily homepage
  JOURNAL   Chem Biol Interact 143-144, 621-631 (2003)
   PUBMED   12604248
REFERENCE   2  (residues 1 to 283)
  AUTHORS   Jez,J.M., Bennett,M.J., Schlegel,B.P., Lewis,M. and Penning,T.M.
  TITLE     Comparative anatomy of the aldo-keto reductase superfamily
  JOURNAL   Biochem J 326 (Pt 3) (Pt 3), 625-636 (1997)
   PUBMED   9307009
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 14442695
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..283
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..283
                     /product="aldo/keto reductase"
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=31332
     Region          4..258
                     /region_name="AKR_AKR5F1"
                     /note="the AKR5F family of aldo-keto reductase (AKR);
                     cd19133"
                     /db_xref="CDD:381359"
     Site            order(18..20,44,48..49,74,107..108,135..136,157,183..189,
                     199,211,226..231,234,237..238)
                     /site_type="active"
                     /db_xref="CDD:381359"
     Site            order(44,49,74,107)
                     /site_type="active"
                     /note="catalytic tetrad [active]"
                     /db_xref="CDD:381359"
ORIGIN      
        1 mktvklnngv evpilgfgty qitdaaeaeh avkdaikagy rhidtaqsym neeavgrgia
       61 asgvdrkelf ittkiwvenv sykgvmssfd rslkrlgldy vdlllihqpf ndvygawiam
      121 eelqasgkir aigvsnfspd rvidlaafne vtpqvnqiev npfqqqtanl ailrkegvai
      181 eawapfaegk ndifnnpvlt kigakygksa aqvilrwlve qdiivlaksv kpermaqnla
      241 ifdfeltead keeiagldqg esqffshadp emvkwmasrk lnv