o-succinylbenzoate synthase [Listeria monocytogenes].

LOCUS       WP_010990009             374 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_010990009
VERSION     WP_010990009.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 374)
  AUTHORS   Palmer,D.R., Garrett,J.B., Sharma,V., Meganathan,R., Babbitt,P.C.
            and Gerlt,J.A.
  TITLE     Unexpected divergence of enzyme function and sequence: 'N-acylamino
            acid racemase' is o-succinylbenzoate synthase
  JOURNAL   Biochemistry 38 (14), 4252-4258 (1999)
   PUBMED   10194342
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01928.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..374
                     /gene="menC"
     Protein         1..374
                     /product="o-succinylbenzoate synthase"
                     /EC_number="4.2.1.113"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41846
     Region          6..359
                     /region_name="NAAAR"
                     /note="N-acylamino acid racemase (NAAAR), an octameric
                     enzyme that catalyzes the racemization of N-acylamino
                     acids. NAAARs act on a broad range of N-acylamino acids
                     rather than amino acids. Enantiopure amino acids are of
                     industrial interest as chiral building...; cd03317"
                     /db_xref="CDD:239433"
     Site            order(19,21,56,162,164,189,214,239,263,291..293)
                     /site_type="active"
                     /db_xref="CDD:239433"
     Site            order(52..56,58,60,66..67,71,86,96..98,112,116..118,123,
                     125,127,129,192,218,220,223,246,249..250,253,275,278..279)
                     /site_type="other"
                     /note="octamer interface [polypeptide binding]"
                     /db_xref="CDD:239433"
ORIGIN      
        1 myfqearlih velpliapfk tsygelnskd fyiielvnee girgygelea fplpdyteet
       61 lstaisivkq hllpilaqke irtpqeinqm fswiqgnema kaavelavwd afakneklsl
      121 akmigaekds iavgvsiglq pdaetlvrlv sqymdegyer vklkiapkkd iqfvkavrek
      181 fpnlslmada nsaynredfw llkeldhfnl emieqpfgak dfvdhawlqk klktriclde
      241 nirslddlkq ahmlgscqav nlklarvggm sealkiakyc sdnnllvwcg gmleagigra
      301 hnialaarae ftfpgdisas nryfnkdivs pafvlnqgkl tvptgqgigv aldldvlqky
      361 tksterilln kgws