MSCRAMM family protein [Listeria monocytogenes].

LOCUS       WP_010989916            1612 aa            linear   BCT 18-FEB-2025
ACCESSION   WP_010989916
VERSION     WP_010989916.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 1612)
  AUTHORS   Foster,T.J.
  TITLE     The MSCRAMM Family of Cell-Wall-Anchored Surface Proteins of
            Gram-Positive Cocci
  JOURNAL   Trends Microbiol 27 (11), 927-941 (2019)
   PUBMED   31375310
REFERENCE   2  (residues 1 to 1612)
  AUTHORS   Foster,T.J.
  TITLE     Surface Proteins of Staphylococcus aureus
  JOURNAL   Microbiol Spectr 7 (4) (2019)
   PUBMED   31267926
REFERENCE   3  (residues 1 to 1612)
  AUTHORS   Deivanayagam,C.C., Wann,E.R., Chen,W., Carson,M., Rajashankar,K.R.,
            Hook,M. and Narayana,S.V.
  TITLE     A novel variant of the immunoglobulin fold in surface adhesins of
            Staphylococcus aureus: crystal structure of the fibrinogen-binding
            MSCRAMM, clumping factor A
  JOURNAL   EMBO J 21 (24), 6660-6672 (2002)
   PUBMED   12485987
REFERENCE   4  (residues 1 to 1612)
  AUTHORS   Smith,D.K. and Xue,H.
  TITLE     Sequence profiles of immunoglobulin and immunoglobulin-like domains
  JOURNAL   J Mol Biol 274 (4), 530-545 (1997)
   PUBMED   9417933
REFERENCE   5  (residues 1 to 1612)
  AUTHORS   Bork,P., Holm,L. and Sander,C.
  TITLE     The immunoglobulin fold. Structural classification, sequence
            patterns and common core
  JOURNAL   J Mol Biol 242 (4), 309-320 (1994)
   PUBMED   7932691
REFERENCE   6  (residues 1 to 1612)
  AUTHORS   Patti,J.M., Allen,B.L., McGavin,M.J. and Hook,M.
  TITLE     MSCRAMM-mediated adherence of microorganisms to host tissues
  JOURNAL   Annu Rev Microbiol 48, 585-617 (1994)
   PUBMED   7826020
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11471690
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1612
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..1612
                     /product="MSCRAMM family protein"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /calculated_mol_wt=174942
     Region          <30..353
                     /region_name="ClfA"
                     /note="Clumping factor A-related surface protein, MSCRAMM
                     (microbial surface components recognizing adhesive matrix
                     molecules) family, DEv-IgG fold [Cell
                     wall/membrane/envelope biogenesis]; COG4932"
                     /db_xref="CDD:443959"
     Region          49..116
                     /region_name="SpaA"
                     /note="Prealbumin-like fold domain; pfam17802"
                     /db_xref="CDD:465513"
     Region          442..549
                     /region_name="Collagen_bind"
                     /note="Collagen binding domain; pfam05737"
                     /db_xref="CDD:283410"
     Region          971..1582
                     /region_name="ClfA"
                     /note="Clumping factor A-related surface protein, MSCRAMM
                     (microbial surface components recognizing adhesive matrix
                     molecules) family, DEv-IgG fold [Cell
                     wall/membrane/envelope biogenesis]; COG4932"
                     /db_xref="CDD:443959"
ORIGIN      
        1 mknirhwkkl viamvigllv fqnvspvlat mtddetantt lkiikedkdt kekingstfe
       61 iknketsets dltisangea tmdsllpgdy lvkekvaakg yaldekeysv tltekeevit
      121 svsakvqeet tkeaatpvkk atqnanlkaa itdnifnkvt lkdgngdein tsdriqngsg
      181 vvlnmnfafs gknykagdtf ttvlpdafnf gnknlsgnfl psteaewsld vttreltitf
      241 lkdgiqegdy dvnistafkv ftsteetiqe vvfktagkdt iyqievvpvv nypttvaita
      301 npgvvnptkg qvdakfnltk ekdakgelkl tdytsggttt idkdsikvys sdvsaggtfi
      361 gtkkllvegt dytltysats ltvtlnggla gkgyqvtydr tinkpsdsls ymstqaytvg
      421 dagtlssnsa yvyltmtnyk hlekkatyng stqsidwkin fnfdqdeisp stvltdvlad
      481 ndveyvadsl kikrvtfnat ngspivgsda ssdwttsais angnfnltyk ntntnayeit
      541 ystkitdfsd rkikneitde ngvsadatia iqpdllkkea gtidyfnntm twkitansdr
      601 ikmgnlnitd efstgvkalk sytvraytdn tnsvlltegk dytidkdvtp agfyiqligd
      661 yastdkkivv dfvtdidlsd vtktidnkas isyydggiik yvdevtasmt pdpgmmtngg
      721 kygsynsttg nidwivsvna maknydnlif ddaiptglty vegslqyrnv astsemmnly
      781 iplnsvgtva ktgdknyptk vdttgnklhl efanlensrv fikystkpne nwyfysyvqn
      841 takvsdngvg eksysyqaya sklfnamtkt atidpsfdnk vnwivtlnni sadrpinnpt
      901 itdtmktgtt gaqvvkssfk vmnettgedi dskyydityt dnnftiqfkd ykatapikvt
      961 ystislmsgl vsntattasp dygslpmtyk srttsispaf tigsgsgtat igsleitkvd
     1021 kkdnskkltg akfqlytleg dkagqeattd sdgkivmdgl qsgkyklvet eaptgytisd
     1081 eykdgkeitv tadiatsvti enteqtgsvv llkedsatkd aiagaefelq nadgtkvadn
     1141 lvsnadgkie vtdlapgdyq fvetkaptgy vldgaptkft vefnqeaavi vtkentaktg
     1201 svvltkedsv skatlsgaef elqnatgtkv kdnlttnadg klevtdlapg dykfvetkap
     1261 tgyeldatpv tftiefnqat avnvtkenva ktgsvvltkl dsksrsnlag aefelqtklg
     1321 vslkdkvvte angqlqidnl apgdyqlvet kaptgydlda tpveftiefn qkapiqvtkt
     1381 ntmstgsvvl tktdgetkal lanatfklvd ednnvtenlt tdasgkleit nlapgdyqli
     1441 etkapagyel dtvpvdvkit fdqketlqvt ktnlktvvsg kviaefvdtk gnvlaekeih
     1501 tgivgdkyat kakdikgykl tkqptnkegv fketeqkvtf vyeknkapiv vnpdkpvtpv
     1561 kptkpvdpak kptvktslps tgdespygii ftglfasfmg lfllrkskki nd