Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

OFA family MFS transporter [Listeria monocytogenes].


LOCUS       WP_010989913             407 aa            linear   BCT 24-MAR-2023
ACCESSION   WP_010989913
VERSION     WP_010989913.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 407)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 407)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024068
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..407
                     /product="OFA family MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42254
     Region          6..392
                     /region_name="MFS_OFA_like"
                     /note="Oxalate:formate antiporter (OFA) and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17353"
                     /db_xref="CDD:340911"
     Site            order(17..18,21..22,25,60,111..112,114..116,119,138,
                     141..142,145,226,229..230,233..235,238,266,270,319..320,
                     324,328,344,347..348,351..352,355)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340911"
ORIGIN      
        1 mtkeinrwgv ligsvgvllc tgavyafsvf agplsaahgw tipqvvmaft inaaigpipt
       61 ilggiltdkg kakwailigg ilfglgfalt gfatsttmly lsygvlaglg qgfaysgcls
      121 ntirlfpdkr glasglitag mggatiiaap ianylietyn vmtafkimga vyiavvigcs
      181 flirvapagy tpkgwtppan nvagmvnvpw tgmvrtvtfy lillmlgiga fsglmiasna
      241 sligqnmfgl taasaaayvs iyslsnclgr vvwgavsdrl grsntlmiiy tvialsllal
      301 ttlqsvvgfv igiiglglcf ggtmgvfpsi vmenygpknq gvnygivfig ystaaffapk
      361 maaqiagqng gdftqafyia ialaavglci nivyklrekk qptkela