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LOCUS WP_010989903 284 aa linear BCT 21-JAN-2025 ACCESSION WP_010989903 VERSION WP_010989903.1 KEYWORDS RefSeq. SOURCE Listeria monocytogenes ORGANISM Listeria monocytogenes Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria. REFERENCE 1 (residues 1 to 284) AUTHORS Nagano,N., Orengo,C.A. and Thornton,J.M. TITLE One fold with many functions: the evolutionary relationships between TIM barrel families based on their sequences, structures and functions JOURNAL J Mol Biol 321 (5), 741-765 (2002) PUBMED 12206759 REFERENCE 2 (residues 1 to 284) AUTHORS Marsh,J.J. and Lebherz,H.G. TITLE Fructose-bisphosphate aldolases: an evolutionary history JOURNAL Trends Biochem Sci 17 (3), 110-113 (1992) PUBMED 1412694 REFERENCE 3 (residues 1 to 284) AUTHORS Perham,R.N. TITLE The fructose-1,6-bisphosphate aldolases: same reaction, different enzymes JOURNAL Biochem Soc Trans 18 (2), 185-187 (1990) PUBMED 2199259 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10097223 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..284 /organism="Listeria monocytogenes" /db_xref="taxon:1639" Protein 1..284 /product="class II fructose-bisphosphate aldolase" /EC_number="4.1.2.13" /GO_function="GO:0004332 - fructose-bisphosphate aldolase activity [Evidence IEA]" /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]" /GO_process="GO:0006096 - glycolytic process [Evidence IEA]" /GO_process="GO:0030388 - fructose 1,6-bisphosphate metabolic process [Evidence IEA]" /calculated_mol_wt=30878 Region 5..281 /region_name="TBP_aldolase_IIB" /note="Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; cd00947" /db_xref="CDD:238477" Site order(26..28,31,51,54,56..57,61,65,68..69,142,233..234, 236..237,240,244,247) /site_type="other" /note="intersubunit interface [polypeptide binding]" /db_xref="CDD:238477" Site order(82..83,177..179,181,208..209,211,230,232..233) /site_type="active" /db_xref="CDD:238477" Site order(83,178,208) /site_type="other" /note="zinc binding site [ion binding]" /db_xref="CDD:238477" Site order(177,179,181,209,211) /site_type="other" /note="Na+ binding site [ion binding]" /db_xref="CDD:238477" ORIGIN 1 myvsmkgmle rankehyavm aincfnleta ravidaaqel rapiiidllq dhltshlgsr 61 fltkpiikma eeasvevain ldhghdvaiv kqcladgfss vmmdassfpy eenvaitkkm 121 vefaevyhas veaevgniga vtgdnytnqe mytdpkvaid fakrtgidal aisygsshgd 181 ypegftpafq fdivreiksa tnmplvlhgg sgcgaenire svrlginkin vgsdfmkaqv 241 nqiktnlkes pavnyvdlih etikagtkav kyyihlsgst gksl