UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [Listeria

LOCUS       WP_010989879             455 aa            linear   BCT 04-JUN-2024
            monocytogenes].
ACCESSION   WP_010989879
VERSION     WP_010989879.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Kouidmi,I., Levesque,R.C. and Paradis-Bleau,C.
  TITLE     The biology of Mur ligases as an antibacterial target
  JOURNAL   Mol Microbiol 94 (2), 242-253 (2014)
   PUBMED   25130693
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Bertrand,J.A., Auger,G., Martin,L., Fanchon,E., Blanot,D., Le
            Beller,D., van Heijenoort,J. and Dideberg,O.
  TITLE     Determination of the MurD mechanism through crystallographic
            analysis of enzyme complexes
  JOURNAL   J Mol Biol 289 (3), 579-590 (1999)
   PUBMED   10356330
REFERENCE   3  (residues 1 to 455)
  AUTHORS   Bertrand,J.A., Auger,G., Fanchon,E., Martin,L., Blanot,D., van
            Heijenoort,J. and Dideberg,O.
  TITLE     Crystal structure of UDP-N-acetylmuramoyl-L-alanine:D-glutamate
            ligase from Escherichia coli
  JOURNAL   EMBO J 16 (12), 3416-3425 (1997)
   PUBMED   9218784
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01087.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..455
                     /gene="murD"
     Protein         1..455
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /EC_number="6.3.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008764 -
                     UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /calculated_mol_wt=50300
     Region          7..450
                     /region_name="MurD"
                     /note="UDP-N-acetylmuramoylalanine-D-glutamate ligase
                     [Cell wall/membrane/envelope biogenesis]; COG0771"
                     /db_xref="CDD:440534"
ORIGIN      
        1 mkkiemyhhk kvlvlglars gvsaatimhk lgafvtvndq kpfsenpeaq glleqgikvi
       61 cgshpielld egfelviknp gipynnpmie kalklkipvi tevelayqis eapivgitgt
      121 ngktttttii hhmlnthken ssllagnigf pasavaenat sdqyismels sfqlmgvetf
      181 kphisvitni yeahldyhtd rseyvqakwh iqknqiaddf lvinwdqeel knltkqtkaq
      241 vipfsttqrl gqgsyvqngn imfndevige rdnillpgeh nlenvlasva vaktlgvtne
      301 eimhvletfk gvehrtqfvv ewqgrkfynd skatnilatq salkgfknpv vllaggldrg
      361 nsfdellpff knvktlivfg etadkigrvg kiagievhyv dnveaavpva yresapgdii
      421 llspacaswd qyrtfevrgn aymdaigeli eevek