Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

SIS domain-containing protein [Listeria monocytogenes].


LOCUS       WP_010989864             331 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_010989864
VERSION     WP_010989864.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 331)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454870
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..331
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..331
                     /product="SIS domain-containing protein"
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=38007
     Region          19..300
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
     Region          37..150
                     /region_name="SIS_1"
                     /note="A subgroup of the SIS domain. SIS (Sugar ISomerase)
                     domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. SIS domains are also found
                     in proteins that regulate the expression of genes involved
                     in synthesis of phosphosugars; cd05710"
                     /db_xref="CDD:240214"
     Site            order(46,91)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:240214"
ORIGIN      
        1 mlkfdeqkvr enmegalklr pqinevvdqi hhrgfsnicw lgiggtyasa mqavvhmkek
       61 taletfyena avflttgnkr vtkdtlvvis svtgstqevv davkkcneig atifgfidka
      121 etelanlvdh lisyplneql kffmvadrfm ylagefedyg afyqemdqhf akgiveveka
      181 adkfgqefal khhqddihyf vgagnqwgat ysyamcywee qhwiktksie sheffhgmfe
      241 iverdtpiti yvtedsqrsl servvnfipq icanytvida kdydmpgisa kfrgalspfi
      301 ihavnnridv hvekinchpm eirryyrqld y