3-isopropylmalate dehydratase large subunit [Listeria

LOCUS       WP_010989859             462 aa            linear   BCT 01-JUL-2024
            monocytogenes].
ACCESSION   WP_010989859
VERSION     WP_010989859.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00170.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..462
                     /gene="leuC"
     Protein         1..462
                     /product="3-isopropylmalate dehydratase large subunit"
                     /EC_number="4.2.1.33"
                     /GO_component="GO:0009316 - 3-isopropylmalate dehydratase
                     complex [Evidence IEA]"
                     /GO_function="GO:0003861 - 3-isopropylmalate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0009098 - L-leucine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=50738
     Region          1..455
                     /region_name="PRK05478"
                     /note="3-isopropylmalate dehydratase large subunit"
                     /db_xref="CDD:235490"
     Site            order(33,36,127..128,401,420,425)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:153133"
     Site            order(129,337,397,400..401,419)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:153133"
ORIGIN      
        1 mgktlfdklw nrhviygkeg epqllyvdlh lihevtspqa feglrlenrp lrrpdktfat
       61 mdhnvptedi fniqdlvakk qiealqtnca efgvtladmg sdrqgivhmv gpetgltqpg
      121 kvivcgdsht athgafgaig fgigsseveh vfatqtiwqq kpksmgiein gklpkgvyak
      181 diilhliaty gvafgtgyav eyygetirnm smeermticn maieggakmg mmapdettfe
      241 yvrgreyapt dmdkaisdwk tlqtdsdaey dlhikmdasi lepyvtwgtn pemgvpfska
      301 fpeikdmnye rayeymglkp gqtaeqielg yvfigsctna rlsdleeaar ivkgnkvknn
      361 iralvvpgsr qvrnaaesig ldkifieagf ewrepgcsmc lgmnpdqvpd gvhcastsnr
      421 nfegrqgkga rthlvspama aaaainghfi dirkvavisg gn