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A/G-specific adenine glycosylase [Listeria monocytogenes].


LOCUS       WP_010989787             365 aa            linear   BCT 02-JUN-2024
ACCESSION   WP_010989787
VERSION     WP_010989787.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Sasaki,M., Yonemura,Y. and Kurusu,Y.
  TITLE     Genetic analysis of Bacillus subtilis mutator genes
  JOURNAL   J Gen Appl Microbiol 46 (3), 183-187 (2000)
   PUBMED   12483591
REFERENCE   2  (residues 1 to 365)
  AUTHORS   Guan,Y., Manuel,R.C., Arvai,A.S., Parikh,S.S., Mol,C.D.,
            Miller,J.H., Lloyd,S. and Tainer,J.A.
  TITLE     MutY catalytic core, mutant and bound adenine structures define
            specificity for DNA repair enzyme superfamily
  JOURNAL   Nat Struct Biol 5 (12), 1058-1064 (1998)
   PUBMED   9846876
REFERENCE   3  (residues 1 to 365)
  AUTHORS   Au,K.G., Clark,S., Miller,J.H. and Modrich,P.
  TITLE     Escherichia coli mutY gene encodes an adenine glycosylase active on
            G-A mispairs
  JOURNAL   Proc Natl Acad Sci U S A 86 (22), 8877-8881 (1989)
   PUBMED   2682664
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01084.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..365
                     /gene="mutY"
     Protein         1..365
                     /product="A/G-specific adenine glycosylase"
                     /EC_number="3.2.2.31"
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /calculated_mol_wt=42025
     Region          12..361
                     /region_name="MutY"
                     /note="Adenine-specific DNA glycosylase, acts on AG and
                     A-oxoG pairs [Replication, recombination and repair];
                     COG1194"
                     /db_xref="CDD:440807"
ORIGIN      
        1 mrkmkrltwd etkitafqea lvswyeankr vlpwrentep yriwvseiml qqtkvdtvip
       61 yfnrfmtqfp tmesfvnade adilkawegl gyysrvrnlq tamkqvmadf sgevptdltt
      121 ilslkgvgpy tagailsiay nqaepavdgn vmrviarvle igedimkast rkifeevlyq
      181 lidkknpaaf nqglmeigal vctptkpmcm lcplqpfcea hkngvetnyp vkikkvkmkt
      241 kellsiivis edgkiaiekr pengllanmw qfptieiskk endevaklqf lhnyglevll
      301 edepiahikh vfshlvwkmd irvaklqsai pnenwyfate eemkrlafpv pyqkmwqawk
      361 dfkge