MFS transporter [Listeria monocytogenes].

LOCUS       WP_010989784             391 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_010989784
VERSION     WP_010989784.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 391)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 391)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 391)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 391)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024677
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..391
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42261
     Region          14..376
                     /region_name="MFS_YcaD_like"
                     /note="YcaD and similar transporters of the Major
                     Facilitator Superfamily; cd17477"
                     /db_xref="CDD:341030"
     Site            order(17..18,21..22,25,57,107..108,110..112,115,135,
                     138..139,142,217,220..221,224..226,229,253,257,306..307,
                     311,315,331,334..335,338..339,342)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341030"
ORIGIN      
        1 mgakgkfwil tmvvaisgls qgvllpliai ileergisag ingfhatgiy lgvllispfi
       61 eaplhkygyk piilvggglv avsilafpiw fnlyfwfilr lligvgdhml hfssqtwiga
      121 msdpskrgrn maiyglffsl gfaigpqlvn laeinanlpf flsgilvlia wglvwfvrnd
      181 fvgekavirk isfwgslkrf sdvfklawva mippflygil etglnatfpv vglrdgldtm
      241 miamvissfs vgtiifqvpi givsdkfgrg kvlplltgag avvfvltafv kipvlyvvff
      301 fvlgillgsl yslglsymtd ltplellpag nilvgmcfsl gsiigpsatg mmigifgnqi
      361 fyfvvagilv lgclllifga rkdalekkmk n