leucine--tRNA ligase [Listeria monocytogenes].

LOCUS       WP_010989774             803 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_010989774
VERSION     WP_010989774.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 803)
  AUTHORS   Liu,Y., Liao,J., Zhu,B., Wang,E.D. and Ding,J.
  TITLE     Crystal structures of the editing domain of Escherichia coli
            leucyl-tRNA synthetase and its complexes with Met and Ile reveal a
            lock-and-key mechanism for amino acid discrimination
  JOURNAL   Biochem J 394 (Pt 2), 399-407 (2006)
   PUBMED   16277600
REFERENCE   2  (residues 1 to 803)
  AUTHORS   Fukunaga,R. and Yokoyama,S.
  TITLE     Aminoacylation complex structures of leucyl-tRNA synthetase and
            tRNALeu reveal two modes of discriminator-base recognition
  JOURNAL   Nat Struct Mol Biol 12 (10), 915-922 (2005)
   PUBMED   16155584
REFERENCE   3  (residues 1 to 803)
  AUTHORS   Zhao,M.W., Zhu,B., Hao,R., Xu,M.G., Eriani,G. and Wang,E.D.
  TITLE     Leucyl-tRNA synthetase from the ancestral bacterium Aquifex
            aeolicus contains relics of synthetase evolution
  JOURNAL   EMBO J 24 (7), 1430-1439 (2005)
   PUBMED   15775966
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00396.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..803
                     /gene="leuS"
     Protein         1..803
                     /product="leucine--tRNA ligase"
                     /EC_number="6.1.1.4"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004823 - leucine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006429 - leucyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /calculated_mol_wt=91765
     Region          1..803
                     /region_name="LeuS"
                     /note="Leucyl-tRNA synthetase [Translation, ribosomal
                     structure and biogenesis]; COG0495"
                     /db_xref="CDD:440261"
ORIGIN      
        1 mtfnhkkmep kwqqywsehn tfkttedknk enfyaldmfp ypsgaglhvg hpegytatdi
       61 lsrmkrmqgk nvlhpigwda fglpaeqyai dtgndpeeft alnianftrq ikslgfsydw
      121 dreinttdpe yykwtqwife klyenglaye aeiavnwcpa lgtvlaneev idgkserggf
      181 pvfrkpmrqw mlkitayadr llddldlvdw penikdmqrn wigrsegaev tfkikdsdet
      241 fnvfttrpdt lfgatytvfa peheliekit tpeqkeavea ykkqvelkse lertdlakdk
      301 tgvftgayai npingeevpi wiadyvliqy gtgaimavpa hderdfefaq qfglnirpvl
      361 eggdvtkeaf tgdgphinsd flnglakaea itaaidwlek egigsrkity rlrdwlfsrq
      421 rywgepipvi hwedgettlv peeelplllp kateikpsgt gesplanlhd wvnvtdengr
      481 kgrretntmp qwagsswyfl ryidpknsea iadkeklaew lpvdvyigga ehavlhllya
      541 rfwhkflydi gvvptkepfq klfnqgmilg ennekmsksr gnvvnpdevv ekygadtlrl
      601 yemfmgplea siawnengle garkfldriw rllvteegtl aekvttdana nlekayhhmv
      661 ktvtnhyenl rfntgisqlm ifineaykqd tipkqyvegf vqllspiaph laeelweilg
      721 htetisyvaw ptydetklve deveivlqvn gkvkskitva kslgkeelek iaqednkmke
      781 nlegktirkv ivvpgklvni van