CBS-HotDog domain-containing transcription factor YtoI [Listeria

LOCUS       WP_010989748             437 aa            linear   BCT 11-JAN-2021
            monocytogenes].
ACCESSION   WP_010989748
VERSION     WP_010989748.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 437)
  AUTHORS   Chen,G.Y., Kao,C.Y., Smith,H.B., Rust,D.P., Powers,Z.M., Li,A.Y.
            and Sauer,J.D.
  TITLE     Mutation of the Transcriptional Regulator YtoI Rescues Listeria
            monocytogenes Mutants Deficient in the Essential Shared Metabolite
            1,4-Dihydroxy-2-Naphthoate (DHNA)
  JOURNAL   Infect Immun 88 (1), e00366-19 (2019)
   PUBMED   31685546
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013726
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..437
                     /gene="ytoI"
     Protein         1..437
                     /product="CBS-HotDog domain-containing transcription
                     factor YtoI"
                     /calculated_mol_wt=48577
     Region          76..178
                     /region_name="DRTGG"
                     /note="DRTGG domain; pfam07085"
                     /db_xref="CDD:429285"
     Region          198..305
                     /region_name="CBS_pair_DRTGG_assoc"
                     /note="Two tandem repeats of the cystathionine
                     beta-synthase (CBS pair) domains associated with the DRTGG
                     domain; cd04596"
                     /db_xref="CDD:341371"
     Site            order(198,200..202,224..226,283,296,298,300..301,304)
                     /site_type="other"
                     /note="putative ligand binding site II [chemical binding]"
                     /db_xref="CDD:341371"
     Region          198..256
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341371"
     Site            order(224,237,241..242,245,261,283..285,300)
                     /site_type="other"
                     /note="putative ligand binding site I [chemical binding]"
                     /db_xref="CDD:341371"
     Region          261..304
                     /region_name="CBS repeat"
                     /note="CBS repeat [structural motif]"
                     /db_xref="CDD:341371"
     Region          339..419
                     /region_name="hot_dog"
                     /note="The hotdog fold was initially identified in the E.
                     coli FabA (beta-hydroxydecanoyl-acyl carrier protein
                     (ACP)-dehydratase) structure and subsequently in 4HBT
                     (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A
                     number of other seemingly unrelated...; cd03440"
                     /db_xref="CDD:239524"
     Site            order(355..356,388..391)
                     /site_type="active"
                     /note="active site 2 [active]"
                     /db_xref="CDD:239524"
     Site            order(361,364..365,368,380..382)
                     /site_type="active"
                     /note="active site 1 [active]"
                     /db_xref="CDD:239524"
ORIGIN      
        1 matkheqilk yienlavgek isvrkiaknl svsegtayra ikdaeiigfv stikrvgtlr
       61 ierkqkdsie kltfaeivnm idgqvlggra glykslnkfv igamtveame rytdagnlli
      121 vgnrvsahel alkrgaavli tggfdtddev kqladekelp ilstsydtft vatminraiy
      181 dqlikkevvf vediltplet taflstsdkv edwhkmeeat ghsrfpvvnr amrltgmvts
      241 kdileknpsi siervmtknp ltvgpkmsva svahmmiwes ievipvvkdd ltligivsrq
      301 dilksmqmiq kqpqvgetid dtianqlsek tdtgeeadye fkvspqmtns lgtlsygvft
      361 qvvcevvqqk lfsmkkrnva ienvtmyflk pvqmdatiii kprilemgrk agkldvelyl
      421 egiltgkaiv acqmmer