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MULTISPECIES: Cd(II)-sensing metalloregulatory transcriptional


LOCUS       WP_010989667             111 aa            linear   BCT 13-OCT-2021
            repressor CadC [Bacilli].
ACCESSION   WP_010989667
VERSION     WP_010989667.1
KEYWORDS    RefSeq.
SOURCE      Bacilli
  ORGANISM  Bacilli
            Bacteria; Bacillati; Bacillota.
REFERENCE   1  (residues 1 to 111)
  AUTHORS   Castro,H., Douillard,F.P., Korkeala,H. and Lindstrom,M.
  TITLE     Mobile Elements Harboring Heavy Metal and Bacitracin Resistance
            Genes Are Common among Listeria monocytogenes Strains Persisting on
            Dairy Farms
  JOURNAL   mSphere 6 (4), e0038321 (2021)
   PUBMED   34232074
REFERENCE   2  (residues 1 to 111)
  AUTHORS   Lee,S., Ward,T.J., Jima,D.D., Parsons,C. and Kathariou,S.
  TITLE     The Arsenic Resistance-Associated Listeria Genomic Island LGI2
            Exhibits Sequence and Integration Site Diversity and a Propensity
            for Three Listeria monocytogenes Clones with Enhanced Virulence
  JOURNAL   Appl Environ Microbiol 83 (21), e01189-17 (2017)
   PUBMED   28842547
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 111)
  AUTHORS   Pombinho,R., Camejo,A., Vieira,A., Reis,O., Carvalho,F.,
            Almeida,M.T., Pinheiro,J.C., Sousa,S. and Cabanes,D.
  TITLE     Listeria monocytogenes CadC Regulates Cadmium Efflux and Fine-tunes
            Lipoprotein Localization to Escape the Host Immune Response and
            Promote Infection
  JOURNAL   J Infect Dis 215 (9), 1468-1479 (2017)
   PUBMED   28368435
REFERENCE   4  (residues 1 to 111)
  AUTHORS   Lebrun,M., Audurier,A. and Cossart,P.
  TITLE     Plasmid-borne cadmium resistance genes in Listeria monocytogenes
            are present on Tn5422, a novel transposon closely related to Tn917
  JOURNAL   J Bacteriol 176 (10), 3049-3061 (1994)
   PUBMED   8188606
REFERENCE   5  (residues 1 to 111)
  AUTHORS   Lebrun,M., Audurier,A. and Cossart,P.
  TITLE     Plasmid-borne cadmium resistance genes in Listeria monocytogenes
            are similar to cadA and cadC of Staphylococcus aureus and are
            induced by cadmium
  JOURNAL   J Bacteriol 176 (10), 3040-3048 (1994)
   PUBMED   8188605
REFERENCE   6  (residues 1 to 111)
  AUTHORS   Ivey,D.M., Guffanti,A.A., Shen,Z., Kudyan,N. and Krulwich,T.A.
  TITLE     The cadC gene product of alkaliphilic Bacillus firmus OF4 partially
            restores Na+ resistance to an Escherichia coli strain lacking an
            Na+/H+ antiporter (NhaA)
  JOURNAL   J Bacteriol 174 (15), 4878-4884 (1992)
   PUBMED   1321115
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR001124
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..111
                     /organism="Bacilli"
                     /db_xref="taxon:91061"
     gene            1..111
                     /gene="cadC"
     Protein         1..111
                     /product="Cd(II)-sensing metalloregulatory transcriptional
                     repressor CadC"
                     /calculated_mol_wt=12349
     Region          30..106
                     /region_name="HTH_metalloreg"
                     /note="metalloregulator ArsR/SmtB family transcription
                     factor; NF033788"
                     /db_xref="CDD:411368"
     Site            order(35..36,40..42,56..58,67..70,72..73,76..77,79..80,
                     86..88,93..95)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238042"
ORIGIN      
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       61 siivkstvat tshhlkilsk agvvqnkkig kmvyyslnns lvetlikdiv l