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MULTISPECIES: signal peptidase II [Bacilli].


LOCUS       WP_010989666             166 aa            linear   BCT 17-OCT-2022
ACCESSION   WP_010989666
VERSION     WP_010989666.1
KEYWORDS    RefSeq.
SOURCE      Bacilli
  ORGANISM  Bacilli
            Bacteria; Bacillati; Bacillota.
REFERENCE   1  (residues 1 to 166)
  AUTHORS   Vogeley,L., El Arnaout,T., Bailey,J., Stansfeld,P.J., Boland,C. and
            Caffrey,M.
  TITLE     Structural basis of lipoprotein signal peptidase II action and
            inhibition by the antibiotic globomycin
  JOURNAL   Science 351 (6275), 876-880 (2016)
   PUBMED   26912896
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00077.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..166
                     /organism="Bacilli"
                     /db_xref="taxon:91061"
     gene            1..166
                     /gene="lspA"
     Protein         1..166
                     /product="signal peptidase II"
                     /EC_number="3.4.23.36"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence
                     IEA]"
                     /calculated_mol_wt=18790
     Region          12..158
                     /region_name="LspA"
                     /note="Lipoprotein signal peptidase [Cell
                     wall/membrane/envelope biogenesis, Intracellular
                     trafficking, secretion, and vesicular transport]; COG0597"
                     /db_xref="CDD:440362"
ORIGIN      
        1 mknktiiskq nlvlivimvg atltdqlski witsnlqlge sieiipsffk ityaqntgaa
       61 wsilegqmtf fyvitlvali llgwyfyrlk dyqiiqkigv almvsgtlgn fidrllfqyv
      121 rdsldfhilg ynfpifnvad vllicgvlfi iidevlksfg vsykkm