glutamine-hydrolyzing GMP synthase [Listeria monocytogenes].

LOCUS       WP_010989661             518 aa            linear   BCT 09-DEC-2019
ACCESSION   WP_010989661
VERSION     WP_010989661.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 518)
  AUTHORS   Tesmer,J.J., Klem,T.J., Deras,M.L., Davisson,V.J. and Smith,J.L.
  TITLE     The crystal structure of GMP synthetase reveals a novel catalytic
            triad and is a structural paradigm for two enzyme families
  JOURNAL   Nat. Struct. Biol. 3 (1), 74-86 (1996)
   PUBMED   8548458
REFERENCE   2  (residues 1 to 518)
  AUTHORS   Tesmer,J.J., Stemmler,T.L., Penner-Hahn,J.E., Davisson,V.J. and
            Smith,J.L.
  TITLE     Preliminary X-ray analysis of Escherichia coli GMP synthetase:
            determination of anomalous scattering factors for a cysteinyl
            mercury derivative
  JOURNAL   Proteins 18 (4), 394-403 (1994)
   PUBMED   8208731
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000848.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00074
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..518
                     /gene="guaA"
     Protein         1..518
                     /product="glutamine-hydrolyzing GMP synthase"
                     /EC_number="6.3.5.2"
                     /function="converts ATP and xanthosine 5'-phosphate and
                     L-glutamine and water to AMP and pyrophosphate diphosphate
                     and GMP and L-glutamate"
                     /GO_function="GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=57983
     Region          11..518
                     /region_name="guaA"
                     /note="GMP synthase; Reviewed; PRK00074"
                     /db_xref="CDD:234614"
ORIGIN      
        1 mfkimkdfte qekiivldfg sqynqlitrr irefgvysel hphtitveem kalnptgiif
       61 sggpnsvyde dafraderif dmgipilgic ygmqlmtthf ggkverakdr eygkadihve
      121 kpnrlfaglp tdqvvwmshg dlvveepagf evtvtskscp iagiadeers lygvqfhpev
      181 rhsvygnell knfalnvcgc kgdwtmenfs eveiakiqei vgdkkvllal sggvdssvvg
      241 vlihkaigdq ltcifvdhgl lrkgeadqvm etlqgefnmn iikvdakkrf mdklagvsdp
      301 eqkrkiigne fiyvfddean kldgveflaq gtlytdiies gtataqtiks hhnvgglped
      361 mqfkliepln tlfkdevral gtelgmpdai vwrqpfpgpg lgirvlgeit eekleivrds
      421 dyilreeikn aglereiwqy ftalpnirsv gvmgdgrtyd htvvvravts idgmtadwar
      481 ipwdvlekis vrivnevdhv nrvvyditsk ppatvewe