N-acetylglucosamine-6-phosphate deacetylase [Listeria

LOCUS       WP_010989627             377 aa            linear   BCT 03-JUN-2024
            monocytogenes].
ACCESSION   WP_010989627
VERSION     WP_010989627.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 377)
  AUTHORS   Hall,R.S., Brown,S., Fedorov,A.A., Fedorov,E.V., Xu,C.,
            Babbitt,P.C., Almo,S.C. and Raushel,F.M.
  TITLE     Structural diversity within the mononuclear and binuclear active
            sites of N-acetyl-D-glucosamine-6-phosphate deacetylase
  JOURNAL   Biochemistry 46 (27), 7953-7962 (2007)
   PUBMED   17567048
REFERENCE   2  (residues 1 to 377)
  AUTHORS   Hall,R.S., Xiang,D.F., Xu,C. and Raushel,F.M.
  TITLE     N-Acetyl-D-glucosamine-6-phosphate deacetylase: substrate
            activation via a single divalent metal ion
  JOURNAL   Biochemistry 46 (27), 7942-7952 (2007)
   PUBMED   17567047
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00221.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..377
                     /gene="nagA"
     Protein         1..377
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /EC_number="3.5.1.25"
                     /GO_function="GO:0008448 - N-acetylglucosamine-6-phosphate
                     deacetylase activity [Evidence IEA]"
                     /GO_process="GO:0006044 - N-acetylglucosamine metabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=41283
     Region          4..373
                     /region_name="NagA"
                     /note="N-acetylglucosamine-6-phosphate deacetylase, NagA,
                     catalyzes the hydrolysis of the N-acetyl group of
                     N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to
                     glucosamine 6-phosphate and acetate. This is the first
                     committed step in the biosynthetic pathway to...; cd00854"
                     /db_xref="CDD:238434"
     Site            order(62,64,129,140,195,213,216..217,248,271,304)
                     /site_type="active"
                     /db_xref="CDD:238434"
     Site            order(215,221,223..224,226,233..234,247..250,252..253,
                     255..256,259)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238434"
ORIGIN      
        1 mankvitnat iytgkgvlen afvrfdkqil evgsmadfqa dkaeevidak gqklvpgfid
       61 vhshggysfd amdadpealr kqvngmlneg ittyfpttmt qsheniekal kvinevaqte
      121 pviggihleg pfvskvfkga qpeeyiqapd lelfkkwfdi sggliklvty apehdtsadf
      181 enlcfelgvv psighsndvr ehlktskath athlynachr mthrepgvpg hvllergina
      241 elivdgihvh pdmvklayqm kgpehlciit dsmrakgmpe gkselggqtv ivkdkqarle
      301 dgtlagsvlt yddgfrnmik ftgcsveeav lmssgnqare fnltqkgaie agkdadfnll
      361 dedlhitaty sfgkkhs