CynX/NimT family MFS transporter [Listeria monocytogenes].

LOCUS       WP_010989624             405 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_010989624
VERSION     WP_010989624.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 405)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 405)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 405)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 405)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   5  (residues 1 to 405)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023805
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..405
                     /product="CynX/NimT family MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43481
     Region          20..396
                     /region_name="MFS_NIMT_CynX_like"
                     /note="2-nitroimidazole and cyanate transporters and
                     similar proteins of the Major Facilitator Superfamily of
                     transporters; cd17339"
                     /db_xref="CDD:340897"
     Site            order(30..31,34..35,38,70,119..120,122..124,127,146,
                     149..150,153,225,228..229,232..234,237,264,268,319..320,
                     324,328,345,348..349,352..353,356)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340897"
ORIGIN      
        1 mnsdltnkki ltrsskvmlv lgivliaanl rtpitsvgpl lgmiqsdlhl tntmaglltt
       61 ipllafagls pfvsklsral gmevlifval ltlvlgsllr pfggelnlfa gtfmiglaia
      121 vgnvilpsli kkefpfklgl mtgvysismn lcaaiaaglt vpiamnnrfs whgsmvfwai
      181 lgivalviwl pqlkynqrst ekiathlvtt svwksplawk islfmgsqsa ifyisiawlp
      241 niladqglss tssglmlslm qfavmpitfi ipiiagrmkn qqllvgisil ffligifgim
      301 fasgsilils iaiiiygigs gmsfslsmmf fnlrttsate sadlsgmaqs igylfaasgp
      361 ilfgtlhdal gswqptlyvl vgitmlmlyc gldagrnkfl fsqkk