MULTISPECIES: MFS transporter [Listeria].

LOCUS       WP_010989601             388 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_010989601
VERSION     WP_010989601.1
KEYWORDS    RefSeq.
SOURCE      Listeria
  ORGANISM  Listeria
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae.
REFERENCE   1  (residues 1 to 388)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 388)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Listeria"
                     /db_xref="taxon:1637"
     Protein         1..388
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41007
     Region          12..382
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(22..23,26..27,30,62,112..113,115..117,120,140,
                     143..144,147,216,219..220,223..225,228,255,259,308..309,
                     313,317,336,339..340,343..344,347)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mdmkkvnpnl tllalaisaf gigstefisv gllplisssm gvsistaglt vsiyalgvmv
       61 gapvlttvta kmnrknllll vmlvflignl vsafavsfgm lltgrvvaaf ahgvfmsias
      121 viaadvvhps krasaiavmf tgltvatvtg vplgtfigql fgwrmsflfi vaigviaiia
      181 nfflvpknls ngksisfksi gqllvnkkiv mvllmtafgy ggtfvvytyl spmfsgmgys
      241 tsmivilliv ygvmvaignt igghfanerp akalfimfsl qgvtllllqf tsgnailglm
      301 timlmgffaf mnvsglqlyv vqlaerylpe tvsmasalni safnigialg afigglvaey
      361 iglsytpivg flmvfiaiil tfymkkdk