LysR family transcriptional regulator [Listeria monocytogenes].

LOCUS       WP_010989491             297 aa            linear   BCT 07-JAN-2025
ACCESSION   WP_010989491
VERSION     WP_010989491.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 297)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444071
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..297
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33795
     Region          3..62
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..288
                     /region_name="PBP2_GltC_like"
                     /note="The substrate binding domain of LysR-type
                     transcriptional regulator GltC, which activates gltA
                     expression of glutamate synthase operon, contains type 2
                     periplasmic binding fold; cd08434"
                     /db_xref="CDD:176125"
     Site            order(107..108,110..111,114,120,122..128,220..225,
                     231..232,234..235)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176125"
ORIGIN      
        1 mnlrqlyyfk klaekehyti aaaelsitqp slshsiaele relgvylfek qgrnirltky
       61 grfyltyvkk slaelekgek llheltspsh gnidlgfiyt mgahtvpelv qnftkveshk
      121 ditfsffqga tksiipdlkn ekfdlaicsy venepdiefl pltkqelvvv vaenhplaky
      181 dsidlqdtad ysyiffsdts glrplidslf aeiniqpkig cyveedtamv glvsvdygis
      241 impkisslah ynvkvlsine pkhdrfiyla slknhyispa skafkdfalr ygkkhfl