Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_010989338 350 aa linear BCT 19-FEB-2025 [Listeria monocytogenes]. ACCESSION WP_010989338 VERSION WP_010989338.1 KEYWORDS RefSeq. SOURCE Listeria monocytogenes ORGANISM Listeria monocytogenes Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria. REFERENCE 1 (residues 1 to 350) AUTHORS Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M. TITLE The many faces of the helix-turn-helix domain: transcription regulation and beyond JOURNAL FEMS Microbiol Rev 29 (2), 231-262 (2005) PUBMED 15808743 REFERENCE 2 (residues 1 to 350) AUTHORS Rosinski,J.A. and Atchley,W.R. TITLE Molecular evolution of helix-turn-helix proteins JOURNAL J Mol Evol 49 (3), 301-309 (1999) PUBMED 10473770 REFERENCE 3 (residues 1 to 350) AUTHORS Wintjens,R. and Rooman,M. TITLE Structural classification of HTH DNA-binding domains and protein-DNA interaction modes JOURNAL J Mol Biol 262 (2), 294-313 (1996) PUBMED 8831795 REFERENCE 4 (residues 1 to 350) AUTHORS Morohoshi,F., Hayashi,K. and Munakata,N. TITLE Molecular analysis of Bacillus subtilis ada mutants deficient in the adaptive response to simple alkylating agents JOURNAL J Bacteriol 173 (24), 7834-7840 (1991) PUBMED 1744039 REFERENCE 5 (residues 1 to 350) AUTHORS Morohoshi,F., Hayashi,K. and Munakata,N. TITLE Bacillus subtilis ada operon encodes two DNA alkyltransferases JOURNAL Nucleic Acids Res 18 (18), 5473-5480 (1990) PUBMED 2120677 REFERENCE 6 (residues 1 to 350) AUTHORS Brennan,R.G. and Matthews,B.W. TITLE The helix-turn-helix DNA binding motif JOURNAL J Biol Chem 264 (4), 1903-1906 (1989) PUBMED 2644244 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11450612 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..350 /organism="Listeria monocytogenes" /db_xref="taxon:1639" Protein 1..350 /product="bifunctional transcriptional activator/DNA repair enzyme AdaA" /EC_number="2.1.1.-" /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_function="GO:0008168 - methyltransferase activity [Evidence IEA]" /GO_process="GO:0006281 - DNA repair [Evidence IEA]" /GO_process="GO:0032259 - methylation [Evidence IEA]" /calculated_mol_wt=39326 Region 1..345 /region_name="AdaA" /note="Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair]; COG2169" /db_xref="CDD:441772" ORIGIN 1 mitnqrdidk yydmlvekns nyegvffvgv kttgilcrpt cpakkplken ceffstakea 61 llasyrpckr ceplsnptkl spavkllvda ieknpekkwt dkdfddlsis antarrqfkk 121 qfgmtfieya rsrrlglafk hirggnsiin aqldsgyesg ngfrdafskt mgevphkskd 181 itilysawle tklgsmlais dddsllllef vdrkgletei kklrmrlnaa itpektiiiq 241 qieaelaqyf ngelidfktp iryigsdfqe nvweelrrip igetisykgl aeklgrstas 301 ravarangan qlslivpchr vintngalgg yggglarkew likhekmvpk