sialidase family protein [Salmonella enterica].

LOCUS       WP_010989000             412 aa            linear   BCT 07-JAN-2025
ACCESSION   WP_010989000
VERSION     WP_010989000.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 412)
  AUTHORS   Coines,J., Raich,L. and Rovira,C.
  TITLE     Modeling catalytic reaction mechanisms in glycoside hydrolases
  JOURNAL   Curr Opin Chem Biol 53, 183-191 (2019)
   PUBMED   31731209
REFERENCE   2  (residues 1 to 412)
  AUTHORS   Naumoff,D.G.
  TITLE     Hierarchical classification of glycoside hydrolases
  JOURNAL   Biochemistry (Mosc) 76 (6), 622-635 (2011)
   PUBMED   21639842
REFERENCE   3  (residues 1 to 412)
  AUTHORS   Vuong,T.V. and Wilson,D.B.
  TITLE     Glycoside hydrolases: catalytic base/nucleophile diversity
  JOURNAL   Biotechnol Bioeng 107 (2), 195-205 (2010)
   PUBMED   20552664
REFERENCE   4  (residues 1 to 412)
  AUTHORS   Taylor,G.
  TITLE     Sialidases: structures, biological significance and therapeutic
            potential
  JOURNAL   Curr Opin Struct Biol 6 (6), 830-837 (1996)
   PUBMED   8994884
REFERENCE   5  (residues 1 to 412)
  AUTHORS   Davies,G. and Henrissat,B.
  TITLE     Structures and mechanisms of glycosyl hydrolases
  JOURNAL   Structure 3 (9), 853-859 (1995)
   PUBMED   8535779
REFERENCE   6  (residues 1 to 412)
  AUTHORS   Henrissat,B., Callebaut,I., Fabrega,S., Lehn,P., Mornon,J.P. and
            Davies,G.
  TITLE     Conserved catalytic machinery and the prediction of a common fold
            for several families of glycosyl hydrolases
  JOURNAL   Proc Natl Acad Sci U S A 92 (15), 7090-7094 (1995)
   PUBMED   7624375
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 1996 May 28;93(11):5674. doi:
            10.1073/pnas.93.11.5674. PMID: 8643635]
REFERENCE   7  (residues 1 to 412)
  AUTHORS   Roggentin,P., Schauer,R., Hoyer,L.L. and Vimr,E.R.
  TITLE     The sialidase superfamily and its spread by horizontal gene
            transfer
  JOURNAL   Mol Microbiol 9 (5), 915-921 (1993)
   PUBMED   7934919
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10202570
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     Protein         1..412
                     /product="sialidase family protein"
                     /EC_number="3.2.1.-"
                     /GO_function="GO:0004308 - exo-alpha-sialidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=45541
     Region          53..402
                     /region_name="Sialidase_non-viral"
                     /note="Non-viral sialidases; cd15482"
                     /db_xref="CDD:271234"
     Region          66..117
                     /region_name="Sialidase propeller 1"
                     /note="Sialidase propeller 1 [structural motif]"
                     /db_xref="CDD:271234"
     Site            order(67,92,261,276,339,372,391)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:271234"
     Region          128..191
                     /region_name="Sialidase propeller 2"
                     /note="Sialidase propeller 2 [structural motif]"
                     /db_xref="CDD:271234"
     Region          203..253
                     /region_name="Sialidase propeller 3"
                     /note="Sialidase propeller 3 [structural motif]"
                     /db_xref="CDD:271234"
     Region          260..296
                     /region_name="Sialidase propeller 4"
                     /note="Sialidase propeller 4 [structural motif]"
                     /db_xref="CDD:271234"
     Region          309..360
                     /region_name="Sialidase propeller 5"
                     /note="Sialidase propeller 5 [structural motif]"
                     /db_xref="CDD:271234"
ORIGIN      
        1 mtrhllncri lymhppldmh thpfikegks mtveksvvfk aegehftdqk gntivgsgsg
       61 gttkyfripa mcttskgtiv vfadarhnta sdqsfidtaa arstdggktw nkkiaiyndr
      121 vnsklsrvmd ptcivaniqg retilvmvgk wnnndktwga yrdkapdtdw dlvlykstdd
      181 gvtfskvetn ihdivtkngt isamlggvgs glqlndgklv fpvqmvrtkn ittvlntsfi
      241 ystdgitwsl psgycegfgs enniiefnas lvnnirnsgl rrsfetkdfg ktwtefppmd
      301 kkvdnrnhgv qgstitipsg nklvaahssa qnknndytrs dislyahnly sgevkliddf
      361 ypkvgnasga gysclsyrkn vdketlyvvy eangsiefqd lsrhlpviks yn