cardiolipin synthase ClsC [Escherichia coli].

LOCUS       WP_010917790             493 aa            linear   BCT 10-FEB-2020
ACCESSION   WP_010917790
VERSION     WP_010917790.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 493)
  AUTHORS   Tan,B.K., Bogdanov,M., Zhao,J., Dowhan,W., Raetz,C.R. and Guan,Z.
  TITLE     Discovery of a cardiolipin synthase utilizing
            phosphatidylethanolamine and phosphatidylglycerol as substrates
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 109 (41), 16504-16509 (2012)
   PUBMED   22988102
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011108
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..493
                     /gene="clsC"
     Protein         1..493
                     /product="cardiolipin synthase ClsC"
                     /EC_number="2.7.8.-"
                     /calculated_mol_wt=55798
     Region          44..204
                     /region_name="PLDc_ymdC_like_1"
                     /note="Putative catalytic domain, repeat 1, of Escherichia
                     coli uncharacterized protein ymdC and similar proteins;
                     cd09111"
                     /db_xref="CDD:197210"
     Site            order(150,152,165,167,183)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197210"
     Site            150
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197210"
     Region          270..489
                     /region_name="PLDc_ymdC_like_2"
                     /note="Putative catalytic domain, repeat 2, of Escherichia
                     coli uncharacterized protein ymdC and similar proteins;
                     cd09113"
                     /db_xref="CDD:197212"
     Site            order(389,391,404,406,417)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:197212"
     Site            389
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:197212"
ORIGIN      
        1 mmkktptstk dslpnkemnd lprlasavlp lcsqhpgqcg lfplekslda faaryrlaem
       61 sehtldvqyy iwqddmsgrl lfsallaaak rgvrvrllld dnntpglddi lrlldshpri
      121 evrlfnpfsf rllrplgyit dfsrlnrrmh nksftvdgvv tlvggrnigd ayfgageepl
      181 fsdldvmaig pvvedvaddf arywycksvs plqqvldvpe gemadrielp aswhndamth
      241 rylrkmessp finhlvdgtl pliwaktrll sddpakgegk akrhsllpqr lfdimgspse
      301 ridiissyfv ptragvaqll rmvrkgvkia iltnslaand vavvhagyar wrkkllrygv
      361 elyelkptre qsstlhdrgi tgnsgaslha ktfsidgktv figsfnfdpr stllntemgf
      421 viesetlaql idkrfiqsqy daawqlrldr wgrinwvdrh akkeivlkke patsfwkrvm
      481 vrlasilpve wll