MULTISPECIES: polysaccharide biosynthesis protein [Pseudomonas].

LOCUS       WP_010895647             665 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_010895647
VERSION     WP_010895647.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 665)
  AUTHORS   Kallberg,Y., Oppermann,U. and Persson,B.
  TITLE     Classification of the short-chain dehydrogenase/reductase
            superfamily using hidden Markov models
  JOURNAL   FEBS J 277 (10), 2375-2386 (2010)
   PUBMED   20423462
REFERENCE   2  (residues 1 to 665)
  AUTHORS   Persson,B., Kallberg,Y., Bray,J.E., Bruford,E., Dellaporta,S.L.,
            Favia,A.D., Duarte,R.G., Jornvall,H., Kavanagh,K.L., Kedishvili,N.,
            Kisiela,M., Maser,E., Mindnich,R., Orchard,S., Penning,T.M.,
            Thornton,J.M., Adamski,J. and Oppermann,U.
  TITLE     The SDR (short-chain dehydrogenase/reductase and related enzymes)
            nomenclature initiative
  JOURNAL   Chem Biol Interact 178 (1-3), 94-98 (2009)
   PUBMED   19027726
REFERENCE   3  (residues 1 to 665)
  AUTHORS   Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the SDR superfamily: functional and structural diversity
            within a family of metabolic and regulatory enzymes
  JOURNAL   Cell Mol Life Sci 65 (24), 3895-3906 (2008)
   PUBMED   19011750
REFERENCE   4  (residues 1 to 665)
  AUTHORS   Ladenstein,R., Winberg,J.O. and Benach,J.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : Structure-function relationships in short-chain alcohol
            dehydrogenases
  JOURNAL   Cell Mol Life Sci 65 (24), 3918-3935 (2008)
   PUBMED   19011748
REFERENCE   5  (residues 1 to 665)
  AUTHORS   Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M.,
            Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H.
  TITLE     Short-chain dehydrogenases/reductases (SDR): the 2002 update
  JOURNAL   Chem Biol Interact 143-144, 247-253 (2003)
   PUBMED   12604210
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 18500220
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..665
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..665
                     /product="polysaccharide biosynthesis protein"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=74285
     Region          133..258
                     /region_name="FlaA1"
                     /note="NDP-sugar epimerase, includes UDP-GlcNAc-inverting
                     4,6-dehydratase FlaA1 and capsular polysaccharide
                     biosynthesis protein EpsC [Cell wall/membrane/envelope
                     biogenesis, Posttranslational modification, protein
                     turnover, chaperones]; COG1086"
                     /db_xref="CDD:440703"
     Region          301..609
                     /region_name="Polysacc_synt_2"
                     /note="Polysaccharide biosynthesis protein; pfam02719"
                     /db_xref="CDD:426938"
     Site            order(305,307..310,330..331,361..363,384..386,388,403,426,
                     442,480..483,486..487)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187548"
     Site            order(331,333,337,341,359..362,365,368,386..389,392,396,
                     399,402,487..488,493)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187548"
     Site            order(388,428..430,438,481..482,488..490,493..494,
                     505..507,511,513,548,581,584)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:187548"
     Site            order(404,428,438,442)
                     /site_type="active"
                     /db_xref="CDD:187548"
ORIGIN      
        1 mldnlrikll glprrykrml qvaadvtlvw lslwlaflvr lgtedmispf sghawlfiaa
       61 plvaiplfir fgmyravmry lgndaliaia kavtisalvl sllvywyrsp pavvprslvf
      121 nywwlsmlli gglrlamrqy fmgdwysavq svpflnrqdg lprvaiygag aagnqlvaal
      181 rlgramrpva fidddkqian rviaglrvyt akhirqmide tgaqevllai psatrarrre
      241 ileslepfpl hvrsmpgfmd lasgrvkvdd lqevdiadll grdsvaprke llercirgqv
      301 vmvtgaggsi gselcrqims cspsvlilfe hseynlysih qelerrikre slsvnllpil
      361 gsvrnperlv dvmrtwkvnt vyhaaaykhv pivehniaeg vlnnvigtlh avqaavqvgv
      421 qnfvlistdk avrptnvmgs tkrlaemvlq alsnesapvl fgdrkdvhhv nktrftmvrf
      481 gnvlgssgsv iplfreqikr ggpvtvthps itryfmtipe aaqlviqags mgqggdvfvl
      541 dmgppvkile laekmihlsg lsvrsersph gdiaiefsgl rpgeklyeel ligdnvnptd
      601 hpmimranee hlsweafkvv leqllaavek ddysrvrqll retvsgyapd geivdwiyrq
      661 rrrep