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elastinolytic metalloprotease LasA [Pseudomonas aeruginosa].


LOCUS       WP_010895585             418 aa            linear   BCT 22-NOV-2021
ACCESSION   WP_010895585
VERSION     WP_010895585.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 418)
  AUTHORS   Spencer,J., Murphy,L.M., Conners,R., Sessions,R.B. and Gamblin,S.J.
  TITLE     Crystal structure of the LasA virulence factor from Pseudomonas
            aeruginosa: substrate specificity and mechanism of M23
            metallopeptidases
  JOURNAL   J Mol Biol 396 (4), 908-923 (2010)
   PUBMED   20026068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to
            AAG05260.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006351
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..418
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..418
                     /gene="lasA"
     Protein         1..418
                     /product="elastinolytic metalloprotease LasA"
                     /calculated_mol_wt=45386
     Region          190..368
                     /region_name="NlpD"
                     /note="Murein DD-endopeptidase MepM and murein hydrolase
                     activator NlpD, contains LysM domain [Cell
                     wall/membrane/envelope biogenesis]; COG0739"
                     /db_xref="CDD:440502"
ORIGIN      
        1 mqhkrsrama sprspflfvl lalavggtan ahddglpafr ysaellgqlq lpsvalplnd
       61 dlflygrdae afdleaylal napalrdkse ylehwsgyys inpkvlltlm vmqsgplgap
      121 deralaaplg rlsakrgfda qvrdvlqqls rryygfeeyq lrqaaarkav gedglnaasa
      181 allgllrega kvsavqggnp lgayaqtfqr lfgtpaaell qpsnrvarql qakaalapps
      241 nlmqlpwrqg yswqpngahs ntgsgypyss fdasydwprw gsatysvvaa hagtvrvlsr
      301 cqvrvthpsg watnyyhmdq iqvsngqqvs adtklgvyag nintalcegg sstgphlhfs
      361 llyngafvsl qgasfgpyri nvgtsnydnd crryyfynqs agtthcafrp lynpglal