ANL family adenylate-forming protein [Pseudomonas aeruginosa].

LOCUS       WP_010895544             428 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_010895544
VERSION     WP_010895544.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 428)
  AUTHORS   Schmelz,S. and Naismith,J.H.
  TITLE     Adenylate-forming enzymes
  JOURNAL   Curr Opin Struct Biol 19 (6), 666-671 (2009)
   PUBMED   19836944
REFERENCE   2  (residues 1 to 428)
  AUTHORS   Gulick,A.M.
  TITLE     Conformational dynamics in the Acyl-CoA synthetases, adenylation
            domains of non-ribosomal peptide synthetases, and firefly
            luciferase
  JOURNAL   ACS Chem Biol 4 (10), 811-827 (2009)
   PUBMED   19610673
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10138310
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..428
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..428
                     /product="ANL family adenylate-forming protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /calculated_mol_wt=47134
     Region          79..415
                     /region_name="AFD_class_I"
                     /note="Adenylate forming domain, Class I, also known as
                     the ANL superfamily; cd04433"
                     /db_xref="CDD:341228"
     Site            order(83,86..91,93..94)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341228"
     Site            order(86,204..205,226..231,309,321,324,335,413)
                     /site_type="other"
                     /note="AMP binding site [chemical binding]"
                     /db_xref="CDD:341228"
     Site            order(86,126..127,177,179..180,183,204..205,226..231,309,
                     321,324,332..335,393)
                     /site_type="active"
                     /db_xref="CDD:341228"
     Site            order(126,179..180,183,204,332..334,387,393)
                     /site_type="other"
                     /note="CoA binding site [chemical binding]"
                     /db_xref="CDD:341228"
ORIGIN      
        1 mlldnsyrnl cliyavmrag khlvlidpew geaakqaivd emrlealase hplegalagl
       61 rlaldfersa trrldraahs hmilftsgtt gqpkgielsq qamlhayrig rdclgigeht
      121 rsgcfyrisg lgilginflf pllyggsavl lplhcwadse gfwecverfg isflylvppv
      181 vnhmvkegsp pprrlplqrl lcvagsarld adlqaafqrd yaalaniygl secgfaflfg
      241 krrgdafdns vgpavglelk ltdpdgrple gsgergrlwv rtpslfsgyv nrpdltaqvl
      301 edgwlntqdl ayfdedrcvh vlgrcdgtin kggnlfhlne ceralnglde vidvcclkvd
      361 cplygedyva vihtapqvef aflpwlqqql gtlrapqrvv lshqalplng agkhdrrala
      421 allqreas