diguanylate cyclase domain-containing protein [Pseudomonas

LOCUS       WP_010895525             735 aa            linear   BCT 26-FEB-2025
            aeruginosa].
ACCESSION   WP_010895525
VERSION     WP_010895525.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 735)
  AUTHORS   Levet-Paulo,M., Lazzaroni,J.C., Gilbert,C., Atlan,D., Doublet,P.
            and Vianney,A.
  TITLE     The atypical two-component sensor kinase Lpl0330 from Legionella
            pneumophila controls the bifunctional diguanylate
            cyclase-phosphodiesterase Lpl0329 to modulate bis-(3'-5')-cyclic
            dimeric GMP synthesis
  JOURNAL   J Biol Chem 286 (36), 31136-31144 (2011)
   PUBMED   21757706
REFERENCE   2  (residues 1 to 735)
  AUTHORS   De,N., Pirruccello,M., Krasteva,P.V., Bae,N., Raghavan,R.V. and
            Sondermann,H.
  TITLE     Phosphorylation-independent regulation of the diguanylate cyclase
            WspR
  JOURNAL   PLoS Biol 6 (3), e67 (2008)
   PUBMED   18366254
REFERENCE   3  (residues 1 to 735)
  AUTHORS   Christen,B., Christen,M., Paul,R., Schmid,F., Folcher,M., Jenoe,P.,
            Meuwly,M. and Jenal,U.
  TITLE     Allosteric control of cyclic di-GMP signaling
  JOURNAL   J Biol Chem 281 (42), 32015-32024 (2006)
   PUBMED   16923812
REFERENCE   4  (residues 1 to 735)
  AUTHORS   Chan,C., Paul,R., Samoray,D., Amiot,N.C., Giese,B., Jenal,U. and
            Schirmer,T.
  TITLE     Structural basis of activity and allosteric control of diguanylate
            cyclase
  JOURNAL   Proc Natl Acad Sci U S A 101 (49), 17084-17089 (2004)
   PUBMED   15569936
REFERENCE   5  (residues 1 to 735)
  AUTHORS   Galperin,M.Y.
  TITLE     Bacterial signal transduction network in a genomic perspective
  JOURNAL   Environ Microbiol 6 (6), 552-567 (2004)
   PUBMED   15142243
REFERENCE   6  (residues 1 to 735)
  AUTHORS   Jenal,U.
  TITLE     Cyclic di-guanosine-monophosphate comes of age: a novel secondary
            messenger involved in modulating cell surface structures in
            bacteria?
  JOURNAL   Curr Opin Microbiol 7 (2), 185-191 (2004)
   PUBMED   15063857
REFERENCE   7  (residues 1 to 735)
  AUTHORS   Paul,R., Weiser,S., Amiot,N.C., Chan,C., Schirmer,T., Giese,B. and
            Jenal,U.
  TITLE     Cell cycle-dependent dynamic localization of a bacterial response
            regulator with a novel di-guanylate cyclase output domain
  JOURNAL   Genes Dev 18 (6), 715-727 (2004)
   PUBMED   15075296
REFERENCE   8  (residues 1 to 735)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
REFERENCE   9  (residues 1 to 735)
  AUTHORS   Pei,J. and Grishin,N.V.
  TITLE     GGDEF domain is homologous to adenylyl cyclase
  JOURNAL   Proteins 42 (2), 210-216 (2001)
   PUBMED   11119645
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013180.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00990.26
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..735
                     /product="diguanylate cyclase domain-containing protein"
                     /EC_number="2.7.7.65"
                     /calculated_mol_wt=82517
     Region          137..299
                     /region_name="CHASE4"
                     /note="CHASE4 domain; pfam05228"
                     /db_xref="CDD:428380"
     Region          369..>733
                     /region_name="COG5001"
                     /note="Cyclic di-GMP metabolism protein, combines GGDEF
                     and EAL domains with a 6TM membrane domain [Signal
                     transduction mechanisms]"
                     /db_xref="CDD:444025"
ORIGIN      
        1 mepsprtaaa vksgacllts tliarllegw vapddarlpe eyaaqvtqpr rciemsnfns
       61 hdrvslcsqp aarlmlspit rphrmplrtr llwlflplla aslggiwlls esillsrfdr
      121 edqqrlqega tvlhnrldfe lkrhldivrt yawwdasydf iqrpnetfeq enldhemldd
      181 lgfdfvlfld drghlqlkqw sppapdqrvl fgapsasdqa llealqqrai rlgaldfrgr
      241 tdhslselll vdnlptllvs vpisnnqgsa pakgailagy fldrerlanl reqmqadlqp
      301 mpniatdstw kplrsrsgst hnqallsprr figehvqqvs vqylsssgep qlrfditkkr
      361 llyiqgekai nfflgasllv algaflvgyl alelwvlrrv qrlnrevaev grnahsirls
      421 dfgndelgql agemnqmler lehseardra ilqsmrdgyf emdvdgvilt vnpalcqllg
      481 qtretlighp yyellgeddl ararqpfqra mqsgagktfa iplqradgsl gyfeatvsli
      541 hdlqgelrgy rgivrdvsdq iayqqqllem ayrdpltglg nrkafdeqlg qallragsgg
      601 selallyldl drfkevndrf ghdigdallr tvaervrstl rqpdkayrlg gdefavlled
      661 sqennpqrla erllaalvqp ialngeridf vtpsigialy prhagdaegl vraadsamye
      721 akrqrnhycl yqapa