MULTISPECIES: pyridoxal phosphate-dependent aminotransferase

LOCUS       WP_010447021             404 aa            linear   BCT 27-MAR-2023
            [Vibrio].
ACCESSION   WP_010447021
VERSION     WP_010447021.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 404)
  AUTHORS   Amadasi,A., Bertoldi,M., Contestabile,R., Bettati,S., Cellini,B.,
            di Salvo,M.L., Borri-Voltattorni,C., Bossa,F. and Mozzarelli,A.
  TITLE     Pyridoxal 5'-phosphate enzymes as targets for therapeutic agents
  JOURNAL   Curr Med Chem 14 (12), 1291-1324 (2007)
   PUBMED   17504214
REFERENCE   2  (residues 1 to 404)
  AUTHORS   Mozzarelli,A. and Bettati,S.
  TITLE     Exploring the pyridoxal 5'-phosphate-dependent enzymes
  JOURNAL   Chem Rec 6 (5), 275-287 (2006)
   PUBMED   17109392
REFERENCE   3  (residues 1 to 404)
  AUTHORS   Mehta,P.K. and Christen,P.
  TITLE     The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes
  JOURNAL   Adv Enzymol Relat Areas Mol Biol 74, 129-184 (2000)
   PUBMED   10800595
REFERENCE   4  (residues 1 to 404)
  AUTHORS   John,R.A.
  TITLE     Pyridoxal phosphate-dependent enzymes
  JOURNAL   Biochim Biophys Acta 1248 (2), 81-96 (1995)
   PUBMED   7748903
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11483700
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     Protein         1..404
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /calculated_mol_wt=45175
     Region          1..404
                     /region_name="PRK09265"
                     /note="aminotransferase AlaT; Validated"
                     /db_xref="CDD:181738"
ORIGIN      
        1 mqnigmsskl dnvcydirgp vlkhakrmee eghkilklni gnpapfgfda pdeilvdvir
       61 nlptsqgycd skgiysarka vvqhyqrkgi rsldvedvyv gngvselivm amqallnngd
      121 emlipapdyp lwtasvalsg gkpvhylcde gadwypdled ikkkitpktr givlinpnnp
      181 tgavysrdfl levieiarqh kliifadeiy dkvlydgath tsvatltedv lvmtfnglsk
      241 ayrvcgfrgg wmfltgpkhl aqgyinglel lssmrlcanv pmqhaiqtal ggyqsineli
      301 lpggrlleqr nrayelinqi pgvscvkpkg amylfpkidt kmynikndqq mvldflkqek
      361 vllvqgsgfn wpkpdhfriv tlphveelet aigrferflt tysq