MULTISPECIES: type 3 dihydrofolate reductase [Vibrio].

LOCUS       WP_010434435             159 aa            linear   BCT 09-DEC-2022
ACCESSION   WP_010434435
VERSION     WP_010434435.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008037.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10769
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..159
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     gene            1..159
                     /gene="folA"
     Protein         1..159
                     /product="type 3 dihydrofolate reductase"
                     /GO_function="GO:0004146 - dihydrofolate reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=17935
     Region          2..159
                     /region_name="DHFR_1"
                     /note="Dihydrofolate reductase; pfam00186"
                     /db_xref="CDD:425512"
     Site            order(6,23,28,58,96,102,115)
                     /site_type="other"
                     /note="folate binding site [chemical binding]"
                     /db_xref="CDD:238127"
     Site            order(8,15,45..47,65,97..100)
                     /site_type="other"
                     /note="NADP+ binding site [chemical binding]"
                     /db_xref="CDD:238127"
ORIGIN      
        1 miismiaama dnrvigkdnq mpwhlpadfa wfkrstmgkp vvmgrktyds igrplpgrln
       61 vvisrdenle iegvttvtsi eqalellnda devmiigggs iyesclpkad klyltyidfv
      121 vdgdtqfpew gegwkqvfse tyqsdeknkh nmefviler