carboxylating nicotinate-nucleotide diphosphorylase [Listeria

LOCUS       WP_009932838             281 aa            linear   BCT 17-JUN-2024
            monocytogenes].
ACCESSION   WP_009932838
VERSION     WP_009932838.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 281)
  AUTHORS   Hughes,K.T., Dessen,A., Gray,J.P. and Grubmeyer,C.
  TITLE     The Salmonella typhimurium nadC gene: sequence determination by use
            of Mud-P22 and purification of quinolinate
            phosphoribosyltransferase
  JOURNAL   J Bacteriol 175 (2), 479-486 (1993)
   PUBMED   8419294
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00078.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..281
                     /gene="nadC"
     Protein         1..281
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /EC_number="2.4.2.19"
                     /GO_function="GO:0004514 - nicotinate-nucleotide
                     diphosphorylase (carboxylating) activity [Evidence IEA]"
                     /GO_process="GO:0009435 - NAD biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=30359
     Region          8..274
                     /region_name="QPRTase"
                     /note="Quinolinate phosphoribosyl transferase (QAPRTase or
                     QPRTase), also called nicotinate-nucleotide
                     pyrophosphorylase, is involved in the de novo synthesis of
                     NAD in both prokaryotes and eukaryotes. It catalyses the
                     reaction of quinolinic acid (QA) with...; cd01572"
                     /db_xref="CDD:238806"
     Site            order(24..25,96..97,101,131,133,137..138,157..158,162,164,
                     166..167,170,181,264)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:238806"
     Site            order(130..132,153..154,215,238..239,258,260..261,264)
                     /site_type="active"
                     /db_xref="CDD:238806"
ORIGIN      
        1 mnsilmnqai qaflledigq ydlsagtvfp rdtmgegvfl aketgilcgi sippkvyell
       61 ggniqfeayk kdgdwvqkgd iiaavkapvr tllsgervil nlmqrmsgia sqtnfaikql
      121 ddsairicdt rktapglraf dkyavqtggg fnhrnglydg vmlkdnhiaf sggitsavst
      181 vrgklghmvk ievetetaeq vkeavqagad iimfdnrtpe eikqlvklvp phitteisgn
      241 vtlenihryk gsganyislg slthsvrafd isfnskggik a