MFS transporter [Listeria monocytogenes].

LOCUS       WP_009932658             406 aa            linear   BCT 30-DEC-2024
ACCESSION   WP_009932658
VERSION     WP_009932658.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 406)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 406)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023689
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..406
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43618
     Region          20..400
                     /region_name="MFS_SLC46_TetA_like"
                     /note="Eukaryotic Solute carrier 46 (SLC46) family,
                     Bacterial Tetracycline resistance proteins, and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17330"
                     /db_xref="CDD:340888"
     Site            order(26..27,30..31,34,70,120..121,123..125,128,147,
                     150..151,154,231,234..235,238..240,243,271,275,328..329,
                     333,337,353,356..357,360..361,364)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340888"
ORIGIN      
        1 mfqsksrtsl tnkktllfgl isvflcgmgf siimpvvpfl vtpyvtnasd qalmvtllts
       61 vyafcvffaa pglgalsdrf grrpvllicf igsaigyfif glggalwvlf lgriiegitg
      121 gsistlfaff aditpqeert kyfgwvsaaa gagaalgpaf ggllahfgya mpfffgatit
      181 finflfgyfy mpeslddanr lkriplmrln pfsqllnilt iknlgrllia affiwvpngs
      241 lqavmsqfai dsfswkpali gmmfsimgiq dilsqafvmp kllirltdkq iavlgmiaei
      301 igysliatss iftlapllvi gmfvfgfgds ifgpsfngmv skaasaseqg riqggsqaiq
      361 slariigpii ggqiyitlgh aapaimgvll itvaifilyk ktslak