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NAD-dependent protein deacylase [Listeria monocytogenes].


LOCUS       WP_009931961             229 aa            linear   BCT 14-MAR-2021
ACCESSION   WP_009931961
VERSION     WP_009931961.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF001752.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00481
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..229
                     /product="NAD-dependent protein deacylase"
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0034979 - NAD-dependent protein
                     deacetylase activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /calculated_mol_wt=25665
     Region          4..226
                     /region_name="SIR2H"
                     /note="Uncharacterized prokaryotic Sir2 homologs from
                     several gram positive bacterial species and Fusobacteria;
                     and are members of the SIR2 family of proteins, silent
                     information regulator 2 (Sir2) enzymes which catalyze
                     NAD+-dependent protein/histone...; cd01411"
                     /db_xref="CDD:238702"
     Site            order(21,23..24,31..32,79,96..97,99,114,180,185,206..207,
                     221)
                     /site_type="other"
                     /note="NAD+ binding site [chemical binding]"
                     /db_xref="CDD:238702"
     Site            order(98,114,152,154..158,184..186)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238702"
     Site            order(122,125,140,143)
                     /site_type="other"
                     /note="putative Zn binding site [ion binding]"
                     /db_xref="CDD:238702"
ORIGIN      
        1 mnklnealkk aerivfltga gvsvpsgipd yrsknglyag msspeymlsh tclvrepekf
       61 yqfvtenmyy pnavpnvihk kmaeietekd vtiitqnidg lhekagskkv vnfhgslyhc
      121 ycqncgmtvt akdylksdih tdcggvirpd vvlyeeaise saidqsltai rkadlivivg
      181 tsfrvspfcn ltdyrnkkar ifavnkeris lpypfemmes davkvfeei