bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine

LOCUS       WP_009931882             267 aa            linear   BCT 15-JUN-2019
            kinase [Listeria monocytogenes].
ACCESSION   WP_009931882
VERSION     WP_009931882.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 267)
  AUTHORS   Mizote,T., Tsuda,M., Smith,D.D., Nakayama,H. and Nakazawa,T.
  TITLE     Cloning and characterization of the thiD/J gene of Escherichia coli
            encoding a thiamin-synthesizing bifunctional enzyme,
            hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
  JOURNAL   Microbiology (Reading, Engl.) 145 (Pt 2), 495-501 (1999)
   PUBMED   10075431
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00097.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..267
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..267
                     /gene="thiD"
     Protein         1..267
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /GO_function="GO:0008902 - hydroxymethylpyrimidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0008972 - phosphomethylpyrimidine kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=28655
     Region          20..260
                     /region_name="ThiD"
                     /note="Hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase [Coenzyme transport and metabolism]; COG0351"
                     /db_xref="CDD:440120"
ORIGIN      
        1 mtfpqvltia gsdsgggagi qadiktfqer rtfgmsvita itaqntlgvk avhkipvemi
       61 reqcdaiaed fqvsavktgm ladaeiirev vrnirlhnfp nlvidpvmia kggtallene
      121 atqvlkdell plgtiitpni peaeeilgek ittkaeiera akkiydmgvk avvikgghse
      181 mteaadfyfd gvtakwltse rfdtphthgt gctfsaciaa elakgnslld svmvakefis
      241 saikyplgig hghgptnhfa yrmedgk