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RecQ family ATP-dependent DNA helicase [Listeria monocytogenes].


LOCUS       WP_009931427             467 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_009931427
VERSION     WP_009931427.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 467)
  AUTHORS   Larsen,N.B. and Hickson,I.D.
  TITLE     RecQ Helicases: Conserved Guardians of Genomic Integrity
  JOURNAL   Adv Exp Med Biol 767, 161-184 (2013)
   PUBMED   23161011
REFERENCE   2  (residues 1 to 467)
  AUTHORS   Rezazadeh,S.
  TITLE     RecQ helicases; at the crossroad of genome replication, repair, and
            recombination
  JOURNAL   Mol Biol Rep 39 (4), 4527-4543 (2012)
   PUBMED   21947842
REFERENCE   3  (residues 1 to 467)
  AUTHORS   Gustafson,E.A. and Wessel,G.M.
  TITLE     DEAD-box helicases: posttranslational regulation and function
  JOURNAL   Biochem Biophys Res Commun 395 (1), 1-6 (2010)
   PUBMED   20206133
REFERENCE   4  (residues 1 to 467)
  AUTHORS   Bernstein,K.A., Gangloff,S. and Rothstein,R.
  TITLE     The RecQ DNA helicases in DNA repair
  JOURNAL   Annu Rev Genet 44, 393-417 (2010)
   PUBMED   21047263
REFERENCE   5  (residues 1 to 467)
  AUTHORS   Chu,W.K. and Hickson,I.D.
  TITLE     RecQ helicases: multifunctional genome caretakers
  JOURNAL   Nat Rev Cancer 9 (9), 644-654 (2009)
   PUBMED   19657341
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11424422
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..467
                     /product="RecQ family ATP-dependent DNA helicase"
                     /EC_number="5.6.2.4"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /calculated_mol_wt=53859
     Region          2..435
                     /region_name="RecQ"
                     /note="Superfamily II DNA helicase RecQ [Replication,
                     recombination and repair]; COG0514"
                     /db_xref="CDD:440280"
ORIGIN      
        1 mnlekelkey lgfdefrpgq kevietalak qncfamlptg tgkticyqla ghlmdglvli
       61 vspllslmqd qmermrahge krvaalnsfl kreekgqila sihsykfifl spemlnnetv
      121 knlllkqkis lfvideahci sqwghdfrpd ylmlgrfiqe akfpvtmvlt atatkkvrad
      181 iltqlhltdc aqivysvnrp nislqvekfs nqhvkkdrly elvrklqtpg iiyfsskkla
      241 estahelsei aelrvayyhg dmdtedriii qqqfvygqld vicatsafgm gidkadiryv
      301 ihyhmpadle aylqeigrag rdgedsvail lyangdefiq mqladqdipd anlmnltteq
      361 rktlpeteqr fidyyqrsgl stkeltdkmd yrkkwkranl qqfigylhtt dcrrnyilry
      421 feeaplevtp enccdldgae iinfekraki kqkeiptwea ylayllq