D-amino-acid transaminase [Listeria monocytogenes].

LOCUS       WP_009931211             289 aa            linear   BCT 10-JUN-2024
ACCESSION   WP_009931211
VERSION     WP_009931211.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 289)
  AUTHORS   Tanizawa,K., Masu,Y., Asano,S., Tanaka,H. and Soda,K.
  TITLE     Thermostable D-amino acid aminotransferase from a thermophilic
            Bacillus species. Purification, characterization, and active site
            sequence determination
  JOURNAL   J Biol Chem 264 (5), 2445-2449 (1989)
   PUBMED   2914916
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01121.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..289
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..289
                     /gene="dat"
     Protein         1..289
                     /product="D-amino-acid transaminase"
                     /EC_number="2.6.1.21"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0047810 - D-alanine:2-oxoglutarate
                     aminotransferase activity [Evidence IEA]"
                     /GO_process="GO:0019480 - L-alanine oxidation to pyruvate
                     via D-alanine [Evidence IEA]"
                     /GO_process="GO:0046416 - D-amino acid metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=32272
     Region          2..279
                     /region_name="D_amino_aminoT"
                     /note="D-amino acid aminotransferase; TIGR01121"
                     /db_xref="CDD:130191"
     Site            order(16..17,19..28,31,88,90,92,112,116,148..152,154..155,
                     158..159,163,182)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:238799"
     Site            order(26,31,50,147,151,179,206..207,243)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:238799"
     Site            order(31,50,147,207,243)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:238799"
     Site            147
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:238799"
ORIGIN      
        1 mkvlvnnhlv eredatvdie drgyqfgdgv yevvrlyngk fftynehidr lyasaakidl
       61 vipyskeelr elleklvaen nintgnvylq vtrgvqnprn hvipddfple gvltaaarev
      121 prnerqfveg gtaiteedvr wlrcdiksln llgnilaknk ahqqnaleai lhrgeqvtec
      181 sasnvsiikd gvlwthaadn lilngitrqv iidvakkngi pvkeadftlt dlreadevfi
      241 ssttieitpi thidgvqvad gkrgpitaql hqyfveeitr acgelvfak