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MFS transporter [Listeria monocytogenes].


LOCUS       WP_009930971             397 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_009930971
VERSION     WP_009930971.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 397)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 397)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 397)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     Protein         1..397
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43222
     Region          10..393
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(24..25,28..29,32,64,115..116,118..120,123,143,
                     146..147,150,223,226..227,230..232,235,263,267,319..320,
                     324,328,344,347..348,351..352,355)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 mnqvkgerhs livllvlfig ytsvyvdkyt igislvtvsq dlgfdpsqkg lilsafflgy
       61 tlfqipmgyl nnrigarpvl aisiiivglf lvifgfgysl lflvvirfls galghagypp
      121 svsnyislhi plnkrgfaqs amlassgfaa figplliaql llsvgwrnty ywigfavili
      181 gflilivvpk apkidlntqk ekikvpfsel lkdkqlwill lsalfinaan ygltswlasy
      241 lnevrgisis evsyisslag lciliagvvg gyfisrffkg kepiiifvfc vlgafavygv
      301 ylfeqlalsv iclclcnifl imafttlmgl phklfqqshi atkyaainsg gvlggffapm
      361 iigdlvnatn syqsaflfla ltllvsgliv laikkdq