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LOCUS WP_009930570 547 aa linear BCT 31-MAR-2023 ACCESSION WP_009930570 VERSION WP_009930570.1 KEYWORDS RefSeq. SOURCE Listeria monocytogenes ORGANISM Listeria monocytogenes Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae; Listeria. REFERENCE 1 (residues 1 to 547) AUTHORS Liu,Y., Guo,X., Liu,W., Wang,J. and Kent Zhao,Z. TITLE Structural Insights into Malic Enzyme Variants Favoring an Unnatural Redox Cofactor JOURNAL Chembiochem 22 (10), 1765-1768 (2021) PUBMED 33523590 REFERENCE 2 (residues 1 to 547) AUTHORS Burley,K.H., Cuthbert,B.J., Basu,P., Newcombe,J., Irimpan,E.M., Quechol,R., Foik,I.P., Mobley,D.L., Beste,D.J.V. and Goulding,C.W. TITLE Structural and Molecular Dynamics of Mycobacterium tuberculosis Malic Enzyme, a Potential Anti-TB Drug Target JOURNAL ACS Infect Dis 7 (1), 174-188 (2021) PUBMED 33356117 REFERENCE 3 (residues 1 to 547) AUTHORS Bologna,F.P., Andreo,C.S. and Drincovich,M.F. TITLE Escherichia coli malic enzymes: two isoforms with substantial differences in kinetic properties, metabolic regulation, and structure JOURNAL J Bacteriol 189 (16), 5937-5946 (2007) PUBMED 17557829 REFERENCE 4 (residues 1 to 547) AUTHORS Wang,J., Tan,H. and Zhao,Z.K. TITLE Over-expression, purification, and characterization of recombinant NAD-malic enzyme from Escherichia coli K12 JOURNAL Protein Expr Purif 53 (1), 97-103 (2007) PUBMED 17215140 REFERENCE 5 (residues 1 to 547) AUTHORS Yang,Z., Zhang,H., Hung,H.C., Kuo,C.C., Tsai,L.C., Yuan,H.S., Chou,W.Y., Chang,G.G. and Tong,L. TITLE Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme JOURNAL Protein Sci 11 (2), 332-341 (2002) PUBMED 11790843 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 11486672 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..547 /organism="Listeria monocytogenes" /db_xref="taxon:1639" Protein 1..547 /product="NAD-dependent malic enzyme" /EC_number="1.1.1.38" /GO_function="GO:0004470 - malic enzyme activity [Evidence IEA]" /GO_function="GO:0004471 - malate dehydrogenase (decarboxylating) (NAD+) activity [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /GO_function="GO:0051287 - NAD binding [Evidence IEA]" /calculated_mol_wt=59907 Region 1..547 /region_name="PRK13529" /note="oxaloacetate-decarboxylating malate dehydrogenase" /db_xref="CDD:237414" ORIGIN 1 mtlksgfdym nnpllnkgta fskeerasyq ldgllppiie tieqqavrie tqienletpl 61 hkhrlltnly nenrtlyyyv vtknvtdylp iiytptigda viqyhkdyta pdealfvdaf 121 apeklsasik nyaknnpnid mivitdgegv lgigdwsvng vkiavgklav ytvaaglapd 181 rvlpvvidag tnnetllndp lylgnkrprl seseydafia sfvnvmkevf pkailhwedf 241 granasrilh nyrdkictfn ddiqgtgamv vaavlatiqv sriplseqki iifgagtagi 301 giadqlsaql mretglpfek akkhfylvdr kglvldnmtd lttgqkkyah psaewsnvpt 361 dtlenlveav hptmligcsg vtgafkesiv kkmtqyterp ailplsnptk laeatasdli 421 qwtdgkaliv tgspskpvey qnttyeigqa nnallypglg lgalvtraky itddmlaaas 481 mavaeqispn kagaallphv rtlretsrav aiavanqaik enihqveltn vieaielemw 541 qpiykgv