multidrug efflux MFS transporter MdrM [Listeria monocytogenes].

LOCUS       WP_009926611             489 aa            linear   BCT 11-APR-2024
ACCESSION   WP_009926611
VERSION     WP_009926611.1
KEYWORDS    RefSeq.
SOURCE      Listeria monocytogenes
  ORGANISM  Listeria monocytogenes
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Listeriaceae;
            Listeria.
REFERENCE   1  (residues 1 to 489)
  AUTHORS   Tadmor,K., Pozniak,Y., Burg Golani,T., Lobel,L., Brenner,M.,
            Sigal,N. and Herskovits,A.A.
  TITLE     Listeria monocytogenes MDR transporters are involved in LTA
            synthesis and triggering of innate immunity during infection
  JOURNAL   Front Cell Infect Microbiol 4, 16 (2014)
   PUBMED   24611134
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 489)
  AUTHORS   Kaplan Zeevi,M., Shafir,N.S., Shaham,S., Friedman,S., Sigal,N., Nir
            Paz,R., Boneca,I.G. and Herskovits,A.A.
  TITLE     Listeria monocytogenes multidrug resistance transporters and cyclic
            di-AMP, which contribute to type I interferon induction, play a
            role in cell wall stress
  JOURNAL   J Bacteriol 195 (23), 5250-5261 (2013)
   PUBMED   24056102
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014718
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Listeria monocytogenes"
                     /db_xref="taxon:1639"
     gene            1..489
                     /gene="mdrM"
     Protein         1..489
                     /product="multidrug efflux MFS transporter MdrM"
                     /calculated_mol_wt=52488
     Region          19..472
                     /region_name="MFS_LmrB_MDR_like"
                     /note="Bacillus subtilis lincomycin resistance protein
                     (LmrB) and similar multidrug resistance (MDR) transporters
                     of the Major Facilitator Superfamily; cd17503"
                     /db_xref="CDD:341046"
     Site            order(26..27,30..31,34,66,116..117,119..121,124,144,
                     147..148,151,275,278..279,282..284,287,315,319,371..372,
                     376,380,396,399..400,403..404,407)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341046"
     Region          135..>247
                     /region_name="PNTB"
                     /note="NAD(P) transhydrogenase beta subunit; cl22917"
                     /db_xref="CDD:473992"
ORIGIN      
        1 mnmkaastsv krngilivml mgafvtilnq tlmnvalpsi mkdfgitasq gqwlstgfml
       61 vngvmipmta flierfttrq lylfamitfa igtaiggfat dytmliagrm vqaigagivm
      121 plltvvvlnl fpmerrgram gliglamnfa paigptlsgw ivqqydwrnl ffiiipfail
      181 divvaifllk nvgkrtfpkl dvlgvimstv gfgslllgfs nagdhdwltw kvagfiilgl
      241 vvlgifiryq tsnkapllnf rvfkyptfal ttaisffvvm glfggmlllp iflqtvrgfs
      301 plesglvllp galvtailsp vtgvmfdrfg akylslvgli imagstfmft nldesttltf
      361 iiivqtirsa gmamvmmplq taalnslplk lashgsamfn tmrqvagsig taalitvmsk
      421 saasfatklg padvigktkt dianhvlihg ietaflvagi lsvvacvlal fiqknrsamd
      481 pivtkteka