amino acid aminotransferase [Vibrio sp. N418].

LOCUS       WP_009386923             396 aa            linear   BCT 07-JAN-2025
ACCESSION   WP_009386923
VERSION     WP_009386923.1
KEYWORDS    RefSeq.
SOURCE      Vibrio sp. N418
  ORGANISM  Vibrio sp. N418
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 396)
  AUTHORS   Christen,P. and Mehta,P.K.
  TITLE     From cofactor to enzymes. The molecular evolution of
            pyridoxal-5'-phosphate-dependent enzymes
  JOURNAL   Chem Rec 1 (6), 436-447 (2001)
   PUBMED   11933250
REFERENCE   2  (residues 1 to 396)
  AUTHORS   Schneider,G., Kack,H. and Lindqvist,Y.
  TITLE     The manifold of vitamin B6 dependent enzymes
  JOURNAL   Structure 8 (1), R1-R6 (2000)
   PUBMED   10673430
REFERENCE   3  (residues 1 to 396)
  AUTHORS   Mehta,P.K. and Christen,P.
  TITLE     The molecular evolution of pyridoxal-5'-phosphate-dependent enzymes
  JOURNAL   Adv Enzymol Relat Areas Mol Biol 74, 129-184 (2000)
   PUBMED   10800595
REFERENCE   4  (residues 1 to 396)
  AUTHORS   Alexander,F.W., Sandmeier,E., Mehta,P.K. and Christen,P.
  TITLE     Evolutionary relationships among pyridoxal-5'-phosphate-dependent
            enzymes. Regio-specific alpha, beta and gamma families
  JOURNAL   Eur J Biochem 219 (3), 953-960 (1994)
   PUBMED   8112347
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10013160
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Vibrio sp. N418"
                     /db_xref="taxon:701176"
     Protein         1..396
                     /product="amino acid aminotransferase"
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /calculated_mol_wt=43019
     Region          1..396
                     /region_name="PRK09257"
                     /note="aromatic amino acid transaminase"
                     /db_xref="CDD:181731"
     Site            order(102..104,130,183,214,243,245..246,254)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99734"
     Site            order(105,140,207,252..254,290,293)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99734"
     Site            246
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99734"
ORIGIN      
        1 mfekvvaapa dpilglteef kkdpraekin lgvgiykneq getpvlatvk kaeaalvete
       61 ktksyltieg tseyglavqk llfgenaeii tdkraktaqa pggtgalrva gefikrqlgd
      121 vkvwvsnptw anhigvftaa gletaqysyy naetkekdfa amvadleqat agdivllhgc
      181 chnptgidpt adewetlaki vaekkllplf dfayqgfgag veddaaglrt fakynkeili
      241 assfsknfgl ynervgaftl vgenedvaat afsqvkaiir siysnppahg aavvtyilnd
      301 aglraeweae vkemrdriqe mrelfvqtlk qqgvdadfsf ierqngmfsf sglnkdqvar
      361 lkdefaiyiv gsgrisvagm tksnmlplcq giaavm