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MFS transporter [Photobacterium leiognathi].


LOCUS       WP_008987382             402 aa            linear   BCT 22-JUL-2024
ACCESSION   WP_008987382
VERSION     WP_008987382.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium leiognathi
  ORGANISM  Photobacterium leiognathi
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 402)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 402)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Photobacterium leiognathi"
                     /db_xref="taxon:553611"
     Protein         1..402
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43326
     Region          14..384
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(23..24,27..28,31,63,113..114,116..118,121,141,
                     144..145,148,222,225..226,229..231,234,262,266,314..315,
                     319,323,338,341..342,345..346,349)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mielhsshyk kacfalalgs fivfcnlylf qpmlplmaqe fgvsatainw vlaattlmla
       61 lclipwaias evvgrrviml vslsllpivg gvmvfsnsll tltilralmg isvagfiava
      121 vaymaeeftp kalmvavgsy isanslggiv grlyggiise hygwhlavlg laifsligav
      181 ivfkllpeqq hfepnrqglq ahskhlvhhl kqpvlwlaml igginfalfv nlysvsgfrl
      241 vaapfnlpls waaliflcyl sgtitakmsg kwanryspis gmllggivsl vgmwlgliev
      301 rsmifvslll issgaffths layawvskna qvakatatam ylvhyyvggs vggflliycw
      361 qhgawggvvt ggtvlygvmf ilcwllakvs ernksllvqs av