MULTISPECIES: porphobilinogen synthase [Photobacterium].

LOCUS       WP_007470989             349 aa            linear   BCT 02-JUN-2019
ACCESSION   WP_007470989
VERSION     WP_007470989.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium
  ORGANISM  Photobacterium
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006762.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09283
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..349
                     /organism="Photobacterium"
                     /db_xref="taxon:657"
     gene            1..349
                     /gene="hemB"
     Protein         1..349
                     /product="porphobilinogen synthase"
                     /EC_number="4.2.1.24"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0004655 - porphobilinogen synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=38530
     Region          7..334
                     /region_name="PRK09283"
                     /note="porphobilinogen synthase"
                     /db_xref="CDD:236450"
     Site            order(13..15,18..19,28..30,54,57,149..150,177..178,
                     207..209,230..231,234..237,240,243..244,262..266,290,305,
                     308,312,315)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:240127"
     Site            order(13,178,244,248)
                     /site_type="other"
                     /note="allosteric magnesium binding site [ion binding]"
                     /db_xref="CDD:240127"
     Site            order(126,128,130,138,174,204,210,213..214,219,228,232,
                     259,282,285,324)
                     /site_type="active"
                     /db_xref="CDD:240127"
     Site            order(130,138,175)
                     /site_type="active"
                     /note="aspartate-rich active site metal binding site
                     [active]"
                     /db_xref="CDD:240127"
     Site            order(204,259)
                     /site_type="active"
                     /note="Schiff base residues [active]"
                     /db_xref="CDD:240127"
ORIGIN      
        1 msvsiqgafp arrmrrmrkh dfsrrlmaen qisvndliyp mfilmgknrr etvdsmpgie
       61 rlsldlmlke aeylaklgvp aialfpvisq dfkstcaaea ynpeglvqra vrllkehvpq
      121 mgvitdvald pftihgqdgi idedgyvmnd ittevlvkqa lshaeagadv vapsdmmdgr
      181 igairealee agyihtqima ysakyasnyy gpfrdavgsa gnlkggdkkt yqmdpansde
      241 alhevamdvn egadmvmvkp gmpyldvvrr vkselqvptf ayqvsgeyam hmaaiqngwl
      301 keretimesl lcfkragadg iltyfaktva ewlaedaaqr kaeldssae