carbamoyl-phosphate synthase large subunit [Photobacterium

LOCUS       WP_007464853            1075 aa            linear   BCT 07-MAY-2024
            marinum].
ACCESSION   WP_007464853
VERSION     WP_007464853.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium marinum
  ORGANISM  Photobacterium marinum
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 1075)
  AUTHORS   Thoden,J.B., Huang,X., Kim,J., Raushel,F.M. and Holden,H.M.
  TITLE     Long-range allosteric transitions in carbamoyl phosphate synthetase
  JOURNAL   Protein Sci 13 (9), 2398-2405 (2004)
   PUBMED   15322282
REFERENCE   2  (residues 1 to 1075)
  AUTHORS   Miles,B.W., Thoden,J.B., Holden,H.M. and Raushel,F.M.
  TITLE     Inactivation of the amidotransferase activity of carbamoyl
            phosphate synthetase by the antibiotic acivicin
  JOURNAL   J Biol Chem 277 (6), 4368-4373 (2002)
   PUBMED   11729189
REFERENCE   3  (residues 1 to 1075)
  AUTHORS   Thoden,J.B., Raushel,F.M., Benning,M.M., Rayment,I. and Holden,H.M.
  TITLE     The structure of carbamoyl phosphate synthetase determined to 2.1 A
            resolution
  JOURNAL   Acta Crystallogr D Biol Crystallogr 55 (Pt 1), 8-24 (1999)
   PUBMED   10089390
REFERENCE   4  (residues 1 to 1075)
  AUTHORS   Thoden,J.B., Holden,H.M., Wesenberg,G., Raushel,F.M. and Rayment,I.
  TITLE     Structure of carbamoyl phosphate synthetase: a journey of 96 A from
            substrate to product
  JOURNAL   Biochemistry 36 (21), 6305-6316 (1997)
   PUBMED   9174345
REFERENCE   5  (residues 1 to 1075)
  AUTHORS   Trotta,P.P., Pinkus,L.M., Haschemeyer,R.H. and Meister,A.
  TITLE     Reversible dissociation of the monomer of glutamine-dependent
            carbamyl phosphate synthetase into catalytically active heavy and
            light subunits
  JOURNAL   J Biol Chem 249 (2), 492-499 (1974)
   PUBMED   4358555
REFERENCE   6  (residues 1 to 1075)
  AUTHORS   Khedouri,E., Anderson,P.M. and Meister,A.
  TITLE     Selective inactivation of the glutamine binding site of Escherichia
            coli carbamyl phosphate synthetase by
            2-amino-4-oxo-5-chloropentanoic acid
  JOURNAL   Biochemistry 5 (11), 3552-3557 (1966)
   PUBMED   5339592
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003671.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05294
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Photobacterium marinum"
                     /db_xref="taxon:1056511"
     gene            1..1075
                     /gene="carB"
     Protein         1..1075
                     /product="carbamoyl-phosphate synthase large subunit"
                     /EC_number="6.3.5.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence
                     IEA]"
                     /calculated_mol_wt=117646
     Region          1..1068
                     /region_name="carB"
                     /note="carbamoyl-phosphate synthase large subunit;
                     PRK05294"
                     /db_xref="CDD:235393"
ORIGIN      
        1 mpkrtdiksv lilgagpivi gqacefdysg aqackalree gyrvilvnsn patimtdpnm
       61 adatyiepih wevvrkiiek erpdavlptm ggqtalncal dlerhgvlde fgvemigata
      121 daidkaedrs rfdaamkaig lecpradtak smeeayqvle mvgfpciirp sftmggtggg
      181 iaynkeefee icrrgldlsp tnellidesl igwkeyemev vrdkndncii vcaienfdpm
      241 gihtgdsitv apaqtltdke yqlmrnasla vlreigvetg gsnvqfginp kdgrmviiem
      301 nprvsrssal askatgfpia kvaaklaigf tldelmndit ggatpasfep tidyvvtkip
      361 rfnfekfaga ndrlttqmks vgevmaigrn qqesmqkalr glevgangfd emvdldapda
      421 ltkirhelkd agaeriwyia dafraglsvd gvfnltnidr wflvqieelv klenqvkegg
      481 faglnaqtlr klkrkgfada rlakllgvae teirklrdqf dihpvykrvd tcaaefssdt
      541 aymyssydee ceanptdnnk imvlgggpnr igqgiefdyc cvhaslalre dgyetimvnc
      601 npetvstdyd tsdrlyfepv tledvlsivr vekpkgvivq yggqtplkla raleaagvpi
      661 igtspdaidr aedrerfqaa verlglkqpe natvtaleqa vekskeigfp lvvrpsyvlg
      721 grameivyde sdlrryfnea vsvsnespvl ldrflddate vdidaicdge nvviggimeh
      781 ieqagvhsgd sacslpaytl sqeiqdvmrq qveklafelg vrglmntqfa vkdnevylie
      841 vnpraartvp fvskatgapl akiaarvmag qslasqgftk eiippyysvk evvlpfnkfp
      901 gvdpllgpem rstgevmgvg ntfaeafaka elgcgkvkqa kgrallsvrg ndkqrvvdla
      961 sklvkqgyel dathgtaivl geaginprlv nkvyegrphi ldriknneyt yivntaegrq
     1021 aiedskvlrr galaekvnyt ttlnaafatc mawsaddrnt vnsvqelhar vksae