histidinol dehydrogenase [Photobacterium marinum].

LOCUS       WP_007461817             441 aa            linear   BCT 17-JUN-2024
ACCESSION   WP_007461817
VERSION     WP_007461817.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium marinum
  ORGANISM  Photobacterium marinum
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00069.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Photobacterium marinum"
                     /db_xref="taxon:1056511"
     gene            1..441
                     /gene="hisD"
     Protein         1..441
                     /product="histidinol dehydrogenase"
                     /EC_number="1.1.1.23"
                     /GO_function="GO:0004399 - histidinol dehydrogenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=47239
     Region          1..424
                     /region_name="hisD"
                     /note="bifunctional histidinal dehydrogenase/ histidinol
                     dehydrogenase; Reviewed; PRK00877"
                     /db_xref="CDD:234853"
     Site            order(55,127,129..130,138,159,182..183,185,206..208,
                     210..211,259)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:119329"
     Site            order(80..81,84..85,87,90..91,94..95,98..99,106,108,
                     112..116,119,121,133..137,201,216,220,247..248,251..252,
                     254..256,258..259,328,333,336..337,339..347,349,351..352,
                     354..358,360,362,372..373,375..379,381..382,385..392,
                     407..408,410..416)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:119329"
     Site            order(135,137,234,259,323..324,353,357..358,364,411,413,
                     416)
                     /site_type="active"
                     /note="product binding site [active]"
                     /db_xref="CDD:119329"
     Site            order(137,234,256,259,323..324,353,357..358,364,411,413,
                     416)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:119329"
     Site            order(256,259,357,416)
                     /site_type="other"
                     /note="zinc binding site [ion binding]"
                     /db_xref="CDD:119329"
     Site            323..324
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:119329"
ORIGIN      
        1 mktvvwqsls etqqeyvlqr paiteganis aivsevidsv rqrgddalle ltekfdkvsp
       61 esikvgteev naaadrlsen mkqalqqayd niaifhkaqk qkplrvetqp gvvceqvtrp
      121 insvglyipg gsaplpstvl mlgvpaqiag crqivlcspp piadeilyva klcgidniyn
      181 vggaqavaam aygtesvikv dkifgpgnaf vteakrqvsn dyrgaaidmp agpsevlvia
      241 dstaepdfia adllsqaehg pdsqvvlvtp epslaervad aiqkqlaela radiarqalg
      301 ssliivadtl mqcvsisnhy gpehlivqtr dprslvsqld nagsiflgnw spesvgdyas
      361 gtnhvlptyg ytrtysslgl adftkrmtvq elnadglqql aptvvtmaea egldahkrav
      421 tirieklqaq qnravankev q