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HIT domain-containing protein [Photobacterium profundum].


LOCUS       WP_006231128             142 aa            linear   BCT 26-FEB-2025
ACCESSION   WP_006231128
VERSION     WP_006231128.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium profundum
  ORGANISM  Photobacterium profundum
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 142)
  AUTHORS   Lima,C.D., Klein,M.G. and Hendrickson,W.A.
  TITLE     Structure-based analysis of catalysis and substrate definition in
            the HIT protein family
  JOURNAL   Science 278 (5336), 286-290 (1997)
   PUBMED   9323207
REFERENCE   2  (residues 1 to 142)
  AUTHORS   Lima,C.D., Klein,M.G., Weinstein,I.B. and Hendrickson,W.A.
  TITLE     Three-dimensional structure of human protein kinase C interacting
            protein 1, a member of the HIT family of proteins
  JOURNAL   Proc Natl Acad Sci U S A 93 (11), 5357-5362 (1996)
   PUBMED   8643579
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013401.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF01230.28
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..142
                     /organism="Photobacterium profundum"
                     /db_xref="taxon:74109"
     Protein         1..142
                     /product="HIT domain-containing protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /calculated_mol_wt=15669
     Region          8..100
                     /region_name="HIT_like"
                     /note="HIT family: HIT (Histidine triad) proteins, named
                     for a motif related to the sequence HxHxH/Qxx (x, a
                     hydrophobic amino acid), are a superfamily of nucleotide
                     hydrolases and transferases, which act on the
                     alpha-phosphate of ribonucleotides. On the basis...;
                     cl00228"
                     /db_xref="CDD:469672"
ORIGIN      
        1 msfilhsrla sdttilgdlp lcqvllskea lgpwlilvpr kedlteihhl pedeqyqlmr
       61 essavaslle nnyqadkinv galgnlvpql hvhhiarfkv dvawpgpvwg ntdgtqrdee
      121 lqlalaedlr vdlsnitgfv sa