MULTISPECIES: phosphoglycerate kinase [Vibrio].

LOCUS       WP_006075685             387 aa            linear   BCT 26-MAR-2023
ACCESSION   WP_006075685
VERSION     WP_006075685.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 387)
  AUTHORS   Chiarelli,L.R., Morera,S.M., Bianchi,P., Fermo,E., Zanella,A.,
            Galizzi,A. and Valentini,G.
  TITLE     Molecular insights on pathogenic effects of mutations causing
            phosphoglycerate kinase deficiency
  JOURNAL   PLoS One 7 (2), e32065 (2012)
   PUBMED   22348148
REFERENCE   2  (residues 1 to 387)
  AUTHORS   Yon,J.M., Desmadril,M., Betton,J.M., Minard,P., Ballery,N.,
            Missiakas,D., Gaillard-Miran,S., Perahia,D. and Mouawad,L.
  TITLE     Flexibility and folding of phosphoglycerate kinase
  JOURNAL   Biochimie 72 (6-7), 417-429 (1990)
   PUBMED   2124145
REFERENCE   3  (residues 1 to 387)
  AUTHORS   Yoshida,A. and Tani,K.
  TITLE     Phosphoglycerate kinase abnormalities: functional, structural and
            genomic aspects
  JOURNAL   Biomed Biochim Acta 42 (11-12), S263-S267 (1983)
   PUBMED   6689547
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10011204
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     Protein         1..387
                     /product="phosphoglycerate kinase"
                     /EC_number="2.7.2.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004618 - phosphoglycerate kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /calculated_mol_wt=40810
     Region          3..383
                     /region_name="pgk"
                     /note="phosphoglycerate kinase; Provisional; PRK00073"
                     /db_xref="CDD:234613"
     Site            order(21,23,36,59,113)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:238195"
     Site            order(178..181,359..361)
                     /site_type="other"
                     /note="hinge regions"
                     /db_xref="CDD:238195"
     Site            order(216,283,307,309,311..314,341..343)
                     /site_type="other"
                     /note="ADP binding site [chemical binding]"
                     /db_xref="CDD:238195"
     Site            342
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:238195"
ORIGIN      
        1 msvikmtdle lagkrvfira dlnvpvkdgk vtsdarilas lptikhclea gakvmvtshl
       61 grptegeyae efslqpvvny lndaldcevk lakdylegle lntgelvvle nvrfnkgekk
      121 neeelskkya alcdifvmda fgtahraqas thgvgmnapv acagpllane lealgkamdk
      181 parpmvaivg gskvstkltv leslskiadq lvvgggiant fiaaaghnvg kslyeadlvd
      241 takklmdeca ipvatdvaca kafdenaeae ikhvsevqdd dmifdlgpds taelakilkd
      301 aktilwngpv gvfefknfea gtegiskaia esdgfsvagg gdtlaaidkf gikadvsyis
      361 tgggaflefv egkvlpavam leeraka