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NupC/NupG family nucleoside CNT transporter [Vibrio mimicus].


LOCUS       WP_005524100             402 aa            linear   BCT 05-JAN-2025
ACCESSION   WP_005524100
VERSION     WP_005524100.1
KEYWORDS    RefSeq.
SOURCE      Vibrio mimicus
  ORGANISM  Vibrio mimicus
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 402)
  AUTHORS   Hirschi,M., Johnson,Z.L. and Lee,S.Y.
  TITLE     Visualizing multistep elevator-like transitions of a nucleoside
            transporter
  JOURNAL   Nature 545 (7652), 66-70 (2017)
   PUBMED   28424521
REFERENCE   2  (residues 1 to 402)
  AUTHORS   Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and
            Lee,S.Y.
  TITLE     Structural basis of nucleoside and nucleoside drug selectivity by
            concentrative nucleoside transporters
  JOURNAL   Elife 3, e03604 (2014)
   PUBMED   25082345
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 402)
  AUTHORS   Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J.
  TITLE     Nucleoside transport in cells and membrane vesicles from
            Escherichia coli K12
  JOURNAL   J Biol Chem 254 (10), 3730-3737 (1979)
   PUBMED   374403
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11449426
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Vibrio mimicus"
                     /db_xref="taxon:674"
     Protein         1..402
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=41853
     Region          1..401
                     /region_name="NupC"
                     /note="Nucleoside permease NupC [Nucleotide transport and
                     metabolism]; COG1972"
                     /db_xref="CDD:441575"
ORIGIN      
        1 mailfgiigv tvlilcayll sesrsainwk tvsralllqi gfaalvlyfp lgqaalssls
       61 ngvsgllsfa digirflfgd ladtgfifai rvlpiiiffs alisalyylg vmqkviafig
      121 ggiqrflgts kaeslvatgn iflsqgespl lvrpflanmt rselfavmag gmasvagsvl
      181 ggyaglgvdl kyliaasfma apgslmmaki ivpergtpid qsqveldkaq dsnlidalas
      241 gamngmkvav avgtmliafv sviamvntgl enlgdmvgfs gitlqalfgy lfaplawvig
      301 vpshevlaag syigqkvvmn efvafidfve hkallsehsq viitfalcgf anigsiaiql
      361 gsigviaper rsdvanlgik avmagtlanl msaclagifi sl