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tRNA lysidine(34) synthetase TilS [Grimontia hollisae].


LOCUS       WP_005506881             440 aa            linear   BCT 23-MAY-2024
ACCESSION   WP_005506881
VERSION     WP_005506881.1
KEYWORDS    RefSeq.
SOURCE      Grimontia hollisae
  ORGANISM  Grimontia hollisae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Grimontia.
REFERENCE   1  (residues 1 to 440)
  AUTHORS   Soma,A., Ikeuchi,Y., Kanemasa,S., Kobayashi,K., Ogasawara,N.,
            Ote,T., Kato,J., Watanabe,K., Sekine,Y. and Suzuki,T.
  TITLE     An RNA-modifying enzyme that governs both the codon and amino acid
            specificities of isoleucine tRNA
  JOURNAL   Mol Cell 12 (3), 689-698 (2003)
   PUBMED   14527414
REFERENCE   2  (residues 1 to 440)
  AUTHORS   Zalacain,M., Biswas,S., Ingraham,K.A., Ambrad,J., Bryant,A.,
            Chalker,A.F., Iordanescu,S., Fan,J., Fan,F., Lunsford,R.D.,
            O'Dwyer,K., Palmer,L.M., So,C., Sylvester,D., Volker,C., Warren,P.,
            McDevitt,D., Brown,J.R., Holmes,D.J. and Burnham,M.K.
  TITLE     A global approach to identify novel broad-spectrum antibacterial
            targets among proteins of unknown function
  JOURNAL   J Mol Microbiol Biotechnol 6 (2), 109-126 (2003)
   PUBMED   15044829
REFERENCE   3  (residues 1 to 440)
  AUTHORS   Muramatsu,T., Yokoyama,S., Horie,N., Matsuda,A., Ueda,T.,
            Yamaizumi,Z., Kuchino,Y., Nishimura,S. and Miyazawa,T.
  TITLE     A novel lysine-substituted nucleoside in the first position of the
            anticodon of minor isoleucine tRNA from Escherichia coli
  JOURNAL   J Biol Chem 263 (19), 9261-9267 (1988)
   PUBMED   3132458
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02432.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..440
                     /organism="Grimontia hollisae"
                     /db_xref="taxon:673"
     gene            1..440
                     /gene="tilS"
     Protein         1..440
                     /product="tRNA lysidine(34) synthetase TilS"
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=48737
     Region          18..434
                     /region_name="AANH_superfamily"
                     /note="Adenine nucleotide alpha hydrolase (AANH)
                     superfamily; cl00292"
                     /db_xref="CDD:469708"
ORIGIN      
        1 mlfslfenvl daytpqprqi vlafsggvds rvmldllaty rdihpqhryl vihihhglsp
       61 nadewmmrce awateadfaf kgirvslnqr egnlenaare aryqailnhv endalvltgq
      121 haddqaetfl lalkrgsgpa glaampvtrp lghavlcrpl lsitravier yaedqglswl
      181 edesnldcrf drnfirqqwl pmaqerwpgm vkainrtarh caeqeallde llsgydhqvm
      241 ladgglsisa lmalsgnmqt amtrrwlkkt agvvpssvqm relqvsvies aqdanpslql
      301 gpvdvrryqg tlyvvpphqd vsawtgqlei getlglpdgl geialqtvgf ggkirapfan
      361 etvsvtfnpe glsahpagrl gkrklkklfq eygvpswerr rtpilfygak iaavaglfvc
      421 egfvggecel vwhkcrafda