multidrug effflux MFS transporter [Photobacterium angustum].

LOCUS       WP_005372416             403 aa            linear   BCT 07-SEP-2024
ACCESSION   WP_005372416
VERSION     WP_005372416.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium angustum
  ORGANISM  Photobacterium angustum
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022939
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Photobacterium angustum"
                     /db_xref="taxon:661"
     Protein         1..403
                     /product="multidrug effflux MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43681
     Region          15..388
                     /region_name="MFS_MdfA_MDR_like"
                     /note="Multidrug transporter MdfA and similar multidrug
                     resistance (MDR) transporters of the Major Facilitator
                     Superfamily; cd17320"
                     /db_xref="CDD:340878"
     Site            order(25..26,29..30,54,57..58,115,146,149..150,232,235,
                     352)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340878"
ORIGIN      
        1 menrvspnin skiqvallit lvlfsplaid iylpalpama ntfsvdptrv qdtvtwfmfs
       61 mglgqllagp ladrigrrpi alggiviygf sstmaylaqs ldllllarll qgfgacatsv
      121 aafaavrdsf gaeksgrmis ylngaicfip alapllgtwl tyhfgwrsnf sfmagfavva
      181 glfimavfke trpansdvsg smisisryws vlreptflfh atlcmlamav ilayvtsapv
      241 wlmnhlgqdm hqftvwfgin avlnitacmv apkfmdrfgt rrtlrtglit llfagglmls
      301 lsqlqqawaf mvpificsfg fafvlgsaag kalapfgdra gtaaallglf qmsgagvmvs
      361 ltqrldfssp vlmtlqmwll ipgllilvsk igrrwhpqlt vqn